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苏丹东部加达里夫医院新生儿重症监护病房的新生儿死亡率及相关因素

Neonatal Mortality and Associated Factors in the Neonatal Intensive Care Unit of Gadarif Hospital, Eastern Sudan.

作者信息

Ahmed Mohammed Ahmed A, Mahgoub Hyder M, Al-Nafeesah Abdullah, Al-Wutayd Osama, Adam Ishag

机构信息

Faculty of Medicine, Gadarif University, Gadarif 32211, Sudan.

Department of Pediatrics, Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah 56219, Saudi Arabia.

出版信息

Children (Basel). 2022 Nov 10;9(11):1725. doi: 10.3390/children9111725.

Abstract

Background: Neonatal mortality is a serious public-health issue, especially in Sub-Saharan African countries. There are limited studies on neonatal mortality in Sudan; particularly, there are none on eastern Sudan. Therefore, this study aimed to determine the incidence, causes and associated factors for mortality among neonates admitted to the neonatal intensive care unit (NICU) of Gadarif Hospital, eastern Sudan. Methods: This retrospective study included 543 neonates admitted to the NICU of Gadarif Hospital, eastern Sudan, between January and August 2019. Data were obtained from the hospital record using a questionnaire composed of sociodemographic data, neonatal and maternal information and neonatal outcomes. Logistic regression analyses were performed and the adjusted odds ratio (AOR) and 95% confidence interval (CI) were calculated. Results: Of the 543 neonates, 50.8% were female, 46.4% were low birth weight (LBW), 43.5% were preterm babies and 27% were newborns admitted after caesarean delivery. The neonatal mortality before discharge was 21.9% (119/543) of live-born babies at the hospital. Preterm birth and its complications (48.7%), respiratory distress syndrome (33.6%), birth asphyxia (21.0%) and infection (9.0%) were the most common causes of neonatal mortality. In multivariable logistic regression analysis, preterm birth (AOR 2.10, 95% CI 1.17−3.74), LBW (AOR 2.47, 95% CI 1.38−4.41), low 5 min APGAR score (AOR 2.59, 95% CI 1.35−4.99) and length of hospital stay <3 days (AOR 5.49, 95% CI 3.44−8.77) were associated with neonatal mortality. Conclusion: There is an increased burden of neonatal mortality in the NICU of Gadarif Hospital, eastern Sudan, predominantly among preterm and LBW babies.

摘要

背景

新生儿死亡率是一个严重的公共卫生问题,尤其是在撒哈拉以南非洲国家。苏丹关于新生儿死亡率的研究有限;特别是在苏丹东部,尚无此类研究。因此,本研究旨在确定苏丹东部加达里夫医院新生儿重症监护病房(NICU)收治的新生儿的死亡率、病因及相关因素。方法:这项回顾性研究纳入了2019年1月至8月间在苏丹东部加达里夫医院NICU收治的543例新生儿。通过一份由社会人口统计学数据、新生儿和母亲信息以及新生儿结局组成的问卷,从医院记录中获取数据。进行逻辑回归分析,并计算调整后的优势比(AOR)和95%置信区间(CI)。结果:在这543例新生儿中,50.8%为女性,46.4%为低出生体重儿(LBW),43.5%为早产儿,27%为剖宫产术后入院的新生儿。医院活产婴儿出院前的新生儿死亡率为21.9%(119/543)。早产及其并发症(48.7%)、呼吸窘迫综合征(33.6%)、出生窒息(21.0%)和感染(9.0%)是新生儿死亡的最常见原因。在多变量逻辑回归分析中,早产(AOR 2.10,95%CI 1.17−3.74)、低出生体重(AOR 2.47,95%CI 1.38−4.41)、5分钟阿氏评分低(AOR 2.59,95%CI 1.35−4.99)和住院时间<3天(AOR 5.49,95%CI 3.44−8.77)与新生儿死亡率相关。结论:苏丹东部加达里夫医院NICU的新生儿死亡率负担加重,主要发生在早产儿和低出生体重儿中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd0a/9688988/5b10e52355d5/children-09-01725-g001.jpg

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