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脑实质内出血:未确诊的急性髓系白血病的致命表现。

Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia.

作者信息

Hamadi Rachelle, Assaad Marc, Zurndorfer Juda, El Gharib Khalil, Kwok Raymond, Dhar Meekoo, Schwab Alfred

机构信息

Internal Medicine, Staten Island University Hospital, New York City, USA.

Neurology, Staten Island University Hospital, New York City, USA.

出版信息

Cureus. 2022 Jun 2;14(6):e25592. doi: 10.7759/cureus.25592. eCollection 2022 Jun.

Abstract

We present the case of a 73-year-old patient who was admitted to the neurocritical care unit with spontaneous intracerebral hemorrhage (ICH). Upon further investigation, she was found to have hyperleukocytosis and thrombocytopenia due to acute myelogenous leukemia (AML), likely resulting in coagulopathy, vessel friability, and consequential intraparenchymal bleed. Prior reports of AML presenting with ICH are scant in the literature. As such, a heightened awareness of such a phenomenon is recommended for rapid detection and appropriate tailored management. This hopefully would, in turn, optimize outcomes.

摘要

我们报告了一例73岁患者,该患者因自发性脑出血入住神经重症监护病房。进一步检查发现,她因急性髓系白血病(AML)导致白细胞增多和血小板减少,这可能导致凝血功能障碍、血管脆性增加,进而引发脑实质内出血。文献中关于AML伴发脑出血的先前报道很少。因此,建议提高对这种现象的认识,以便快速检测并进行适当的针对性管理。这有望反过来优化治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6049/9250100/76d6516a90eb/cureus-0014-00000025592-i01.jpg

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