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合并左心室血栓的心室心肌致密化不全:一例报告

Ventricular Noncompaction With Left Ventricular Thrombus: A Case Report.

作者信息

Alrefaee Anas, Wiseman Kyle, Udongwo Ndausung, Sathya Bharath, Demchuk Beverly

机构信息

Cardiology, Jersey Shore University Medical Center, Neptune, USA.

Internal Medicine, Jersey Shore University Medical Center, Neptune, USA.

出版信息

Cureus. 2022 Jun 2;14(6):e25605. doi: 10.7759/cureus.25605. eCollection 2022 Jun.

DOI:10.7759/cureus.25605
PMID:35795525
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9250348/
Abstract

Noncompaction cardiomyopathy (NCC) is congenital cardiomyopathy characterized by trabeculations of the left ventricle found on echocardiogram and/or cardiac magnetic resonance imaging (CMRI). This rare disease is associated with thromboembolism and an increased risk of ventricular thrombus formation. We present the case of a 73-year-old female who was admitted for a suspected cerebrovascular accident (CVA), later found on echocardiogram and CMRI to have NCC with left ventricular thrombus. She was started on warfarin indefinitely. We highlight the rarity of this phenomenon as well as the unique questions regarding initiation, length, and choice of therapeutic anticoagulation in the absence of atrial fibrillation in these patients. Consideration of this diagnosis should be made in the absence of other cardioembolic etiologies with prompt management based on available guidelines.

摘要

非致密化型心肌病(NCC)是一种先天性心肌病,其特征为在超声心动图和/或心脏磁共振成像(CMRI)上发现左心室小梁增多。这种罕见疾病与血栓栓塞及心室血栓形成风险增加有关。我们报告了一例73岁女性患者,因疑似脑血管意外(CVA)入院,后来经超声心动图和CMRI检查发现患有NCC并伴有左心室血栓。她开始长期服用华法林。我们强调了这种现象的罕见性,以及在这些无房颤患者中启动、疗程和治疗性抗凝选择方面的独特问题。在没有其他心源性栓塞病因的情况下,应考虑这一诊断,并根据现有指南进行及时处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/23971025df9f/cureus-0014-00000025605-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/1e28d1db52f6/cureus-0014-00000025605-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/39bc6ad3523b/cureus-0014-00000025605-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/7baa1c465f80/cureus-0014-00000025605-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/23971025df9f/cureus-0014-00000025605-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/1e28d1db52f6/cureus-0014-00000025605-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/39bc6ad3523b/cureus-0014-00000025605-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/7baa1c465f80/cureus-0014-00000025605-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c870/9250348/23971025df9f/cureus-0014-00000025605-i04.jpg

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2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.《2021年卒中与短暂性脑缺血发作患者卒中预防指南:美国心脏协会/美国卒中协会指南》
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Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.
直接口服抗凝剂与华法林在左心室血栓中的应用比较。
JAMA Cardiol. 2020 Jun 1;5(6):685-692. doi: 10.1001/jamacardio.2020.0652.
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Eur Heart J Case Rep. 2019 Dec 31;4(1):1-6. doi: 10.1093/ehjcr/ytz215. eCollection 2020 Feb.
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Efficacy of Direct Acting Oral Anticoagulants in Treatment of Left Ventricular Thrombus.直接口服抗凝剂治疗左心室血栓的疗效。
Am J Cardiol. 2019 Aug 1;124(3):367-372. doi: 10.1016/j.amjcard.2019.05.009. Epub 2019 May 8.
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2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy.2019 HRS 专家共识声明:心律失常性心肌病的评估、风险分层和管理。
Heart Rhythm. 2019 Nov;16(11):e301-e372. doi: 10.1016/j.hrthm.2019.05.007. Epub 2019 May 9.
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