Marchegiani Andrea, Fruganti Alessandro, Gavazza Alessandra, Spaterna Andrea, Cerquetella Matteo
School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy.
Front Vet Sci. 2022 Jun 20;9:880349. doi: 10.3389/fvets.2022.880349. eCollection 2022.
Interdigital furunculosis is a common multifactorial, inflammatory disease of the canine interdigital skin in which lesions commonly become secondarily infected. Fluorescence biomodulation (FBM) administered twice weekly has shown to effectively control clinical manifestation as adjunct therapy to systemic antibiotic. Since twice weekly regimen could be unaffordable for some pet owners, the aim of this study was to evaluate the effect of once weekly application of FBM in combination with systemic antibiotic on clinical manifestations of canine interdigital pyoderma, comparing the results to those present in literature. Twelve dogs diagnosed with interdigital pyoderma received antibiotic plus once weekly FBM application. Dogs were scored until complete healing based on global lesion score and neutrophil engulfing bacterial score. The results obtained demonstrated that once weekly application of FBM exerts the same beneficial effect on interdigital furunculosis healing as per twice weekly, indicating that once weekly regimen is well tolerated and is yielding similar results to twice weekly applications.
指间疖病是犬指间皮肤常见的多因素炎症性疾病，其病变通常会继发感染。每周两次进行荧光生物调制（FBM）已显示出作为全身抗生素辅助治疗可有效控制临床表现。由于每周两次的治疗方案对一些宠物主人来说可能难以承受，本研究的目的是评估每周一次应用FBM联合全身抗生素对犬指间脓皮病临床表现的影响，并将结果与文献中的结果进行比较。12只被诊断为指间脓皮病的犬接受抗生素加每周一次的FBM治疗。根据整体病变评分和中性粒细胞吞噬细菌评分对犬进行评分，直至完全愈合。获得的结果表明，每周一次应用FBM对指间疖病愈合的有益效果与每周两次相同，这表明每周一次的治疗方案耐受性良好，且产生的结果与每周两次应用相似。
