Mannis M J, Morrison T L, Zadnik K, Holland E J, Krachmer J H
Arch Ophthalmol. 1987 Jun;105(6):798-800. doi: 10.1001/archopht.1987.01060060084038.
Patients with keratoconus frequently are described as having peculiar personality characteristics, despite the lack of controlled studies in the ophthalmologic or psychiatric literature. We studied 109 subjects, using a standardized personality inventory (the Millon Clinical Multiaxial Inventory) that measures 20 personality scales-both normal and pathologic. Subjects were divided into three age-matched groups: (1) patients with keratoconus, (2) patients with other chronic eye diseases, and (3) normal controls. Results indicated that although chronic eye disease, including keratoconus, did have an impact on personality functioning in young and middle-aged adults, no specific complex of personality characteristics attributable to keratoconus could be identified. Patients with keratoconus differed from normal controls in much the same way as did patients with other chronic eye diseases, being less conforming and more passive-aggressive, paranoid, and hypomanic. They tended to more disorganized patterns of thinking and scored higher on substance abuse indicators. The influence of keratoconus on personality may be a function of the timing and nature of its onset in the context of the patient's psychosocial development.
尽管眼科或精神病学文献中缺乏对照研究，但圆锥角膜患者常被描述为具有特殊的人格特征。我们使用标准化人格量表（米隆临床多轴量表）对109名受试者进行了研究，该量表可测量20种人格维度，包括正常和病理维度。受试者被分为三个年龄匹配组：（1）圆锥角膜患者，（2）其他慢性眼病患者，（3）正常对照组。结果表明，尽管包括圆锥角膜在内的慢性眼病确实对青年和中年成年人的人格功能有影响，但无法确定任何归因于圆锥角膜的特定人格特征组合。圆锥角膜患者与正常对照组的差异，与其他慢性眼病患者与正常对照组的差异大致相同，即他们更不循规蹈矩，更具被动攻击性、偏执和轻度躁狂倾向。他们的思维模式往往更混乱，在药物滥用指标上得分更高。圆锥角膜对人格的影响可能取决于其在患者心理社会发展背景下的发病时间和性质。
