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本文引用的文献

1
COVID-19-associated mucormycosis: Case report and systematic review.COVID-19 相关毛霉病:病例报告和系统评价。
Travel Med Infect Dis. 2021 Nov-Dec;44:102148. doi: 10.1016/j.tmaid.2021.102148. Epub 2021 Aug 26.
2
Mucormycosis and COVID-19: An epidemic within a pandemic in India.毛霉菌病与 COVID-19:印度大流行中的一场流行病。
Mycoses. 2021 Oct;64(10):1253-1260. doi: 10.1111/myc.13353. Epub 2021 Jul 24.
3
Invasive mould disease in fatal COVID-19: a systematic review of autopsies.COVID-19 致死患者的侵袭性霉菌病:尸检的系统回顾。
Lancet Microbe. 2021 Aug;2(8):e405-e414. doi: 10.1016/S2666-5247(21)00091-4. Epub 2021 Jun 23.
4
Autopsy Proven Pulmonary Mucormycosis Due to in a Critically Ill COVID-19 Patient with Underlying Hematological Malignancy.一名患有基础血液系统恶性肿瘤的危重症COVID-19患者尸检证实的由毛霉菌引起的肺毛霉病
J Fungi (Basel). 2021 Jan 27;7(2):88. doi: 10.3390/jof7020088.
5
The Postmortem Features of Mucormycosis.毛霉菌病的尸检特征
Acad Forensic Pathol. 2020 Jun;10(2):72-80. doi: 10.1177/1925362120960918. Epub 2020 Nov 25.
6
Epidemiology and clinical manifestations of mucormycosis.毛霉病的流行病学和临床表现。
Clin Infect Dis. 2012 Feb;54 Suppl 1:S23-34. doi: 10.1093/cid/cir866.
7
Pathogenesis of mucormycosis.毛霉病的发病机制。
Clin Infect Dis. 2012 Feb;54 Suppl 1(Suppl 1):S16-22. doi: 10.1093/cid/cir865.
8
A higher-level phylogenetic classification of the Fungi.真菌的高级系统发育分类
Mycol Res. 2007 May;111(Pt 5):509-47. doi: 10.1016/j.mycres.2007.03.004. Epub 2007 Mar 13.
9
Novel perspectives on mucormycosis: pathophysiology, presentation, and management.毛霉菌病的新视角:病理生理学、临床表现及治疗
Clin Microbiol Rev. 2005 Jul;18(3):556-69. doi: 10.1128/CMR.18.3.556-569.2005.

一名新冠病毒检测呈阳性患者的肺炎和肺毛霉病——病例报告

Pneumonitis and Pulmonary Mucormycosis in a Covid-19 Positive Patient-A Case Report.

作者信息

Sharma Luv, Gupta Sumiti, Chopra Lalit, Dhamija Pooja

出版信息

Acad Forensic Pathol. 2022 Jun;12(2):58-64. doi: 10.1177/19253621221106885. Epub 2022 Jun 15.

DOI:10.1177/19253621221106885
PMID:35799994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9254015/
Abstract

In the wake of second wave of coronavirus disease (Covid-19), an increased number of mucormycosis cases were reported by the Ministry of Health and Family Welfare in India. A total of 45 432 cases of mucormycosis were reported till mid-July 2021, with 4252 fatalities. Mucormycosis and other fungal infections are most commonly seen as an opportunistic infection. They are found in those with low underlying immunity either due to a diabetes, cancers particularly hematological malignancies, and so on, or as a side effect of prolonged/irrational use of certain drugs like steroids, immunosuppressive drugs for management of other disorders including Covid-19. The Health Authorities in India stated that although it is not a new disease, its true incidence during the beginning of the second wave was unknown as it was not a notifiable disease. As per reports, the most common presentations of mucormycosis included rhinocerebral (77.6%), cutaneous (4.3%), and pulmonary (3.0%). We present a case of pulmonary mucormycosis and pneumonitis in a Covid-19 positive patient brought for autopsy. The patient was an under trial prisoner sent for treatment to our facility who was reported Covid positive.

摘要

在新冠疫情第二波来袭之后,印度卫生和家庭福利部报告的毛霉菌病病例有所增加。截至2021年7月中旬,共报告了45432例毛霉菌病病例,其中4252例死亡。毛霉菌病和其他真菌感染最常见的是机会性感染。它们见于那些由于糖尿病、癌症尤其是血液系统恶性肿瘤等导致基础免疫力低下的人群,或者是由于长期/不合理使用某些药物(如类固醇、用于治疗包括新冠在内的其他疾病的免疫抑制药物)的副作用。印度卫生当局表示,尽管这不是一种新疾病,但在第二波疫情开始时其真实发病率未知,因为它不是法定报告疾病。据报告,毛霉菌病最常见的表现包括鼻脑型(77.6%)、皮肤型(4.3%)和肺型(3.0%)。我们报告一例新冠阳性患者尸检时发现的肺毛霉菌病和肺炎病例。该患者是一名候审囚犯,被送往我们的机构接受治疗,报告新冠检测呈阳性。