Ding Lin, Ding Shuang, He Chunmei, Zhang Qifa, An Jingjing
Operating Room, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.
Department of Nuclear Medicine, Fuwai Yunnan Cardiovascular Hospital, Kunming, China.
Gland Surg. 2022 Jun;11(6):1078-1085. doi: 10.21037/gs-22-258.
This study systematically reviewed the effects of continuous nursing intervention on intraoperative pressure ulcers (PUs) and related complications in breast cancer patients. The effectiveness of continuous nursing intervention for intraoperative pressure ulcers related complications in breast cancer patients is highly controversial. Therefore, it is necessary to systematically review and address this issue by means of meta-analysis.
By searching the Cochrane Library, PubMed, Web of Science, Embase, and Chinese Biomedical Literature Database (CBM) were screened. Quality evaluation and data extraction were performed for the included studies, and meta-analysis was performed for the included RCTs using Review Manager 5.2 software. Literature was included in strict compliance with the PICOS principle, and bias risk was analyzed by -test and funnel plot.
A total of 1,431 patients were enrolled in 9 studies, and meta-analysis showed that there was a significant statistical difference between the experimental group and the control group in the incidence of PUs [odds ratio (OR) =0.18, 95% confidence interval (95% CI): 0.13-0.24, P<0.00001], the Braden pressure ulcer risk score after nursing [mean difference (MD) =2.64, 95% CI: 1.47-3.81, P<0.0001], and the quality of life after nursing (MD =9.76, 95% CI: 6.82-12.69, P<0.00001).
Continuous care can reduce the incidence of PUs in patients with advanced breast cancer, reduce the severity of wounds in the healing process of PUs, and improve the knowledge of PUs in patients with advanced breast cancer risk.
本研究系统评价了连续性护理干预对乳腺癌患者术中压疮及相关并发症的影响。连续性护理干预对乳腺癌患者术中压疮相关并发症的有效性存在高度争议。因此，有必要通过荟萃分析对这一问题进行系统评价并加以解决。
通过检索考克兰图书馆、PubMed、Web of Science、Embase以及中国生物医学文献数据库（CBM）进行筛选。对纳入研究进行质量评价和数据提取，使用Review Manager 5.2软件对纳入的随机对照试验进行荟萃分析。严格按照PICOS原则纳入文献，并通过检验和漏斗图分析偏倚风险。
9项研究共纳入1431例患者，荟萃分析显示，试验组与对照组在压疮发生率[比值比（OR）=0.18，95%置信区间（95%CI）：0.13-0.24，P<0.00001]、护理后Braden压疮风险评分[平均差（MD）=2.64，95%CI：1.47-3.81，P<0.0001]以及护理后生活质量（MD =9.76，95%CI：6.82-12.69，P<0.00001）方面存在显著统计学差异。
连续性护理可降低晚期乳腺癌患者压疮的发生率，减轻压疮愈合过程中伤口的严重程度，并提高晚期乳腺癌风险患者对压疮的认知。
