Nurakysh Saule, Kurakbayev Kural, Kosherbaeva Lyazzat, Tazhiyeva Aigul, Aimakhanova Aizat, Kulkaeva Gulnara, Asykbaeva Lyazzat, Ainabekov Marat, Fakhradiyev Ildar, Tanabayeva Shynar
S.D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Kazakhstan's Medical University "KSPH" LLP, Almaty, Kazakhstan.
Acta Inform Med. 2022 Mar;30(1):18-24. doi: 10.5455/aim.2022.30.18-24.
An assessment of the level of adherence of patients diagnosed with hypertension to therapy has not been conducted in Central Asia yet. It includes the lack the information on the impact of digital technologies on hypertension management.
The study aimed at the evaluation of the effect of using a mobile application on adherence to therapy in patients with diagnosed arterial hypertension.
A multi-centre randomized controlled study was conducted on 517 patients with diagnosed arterial hypertension (in the out-patient clinic, Almaty, Kazakhstan). Patients were randomly assigned to intervention (IG) and control (CG) groups. IG patients used a mobile application, which allowed creating an individual schedule for taking medications, including visual and audio notifications. The assessment of adherence to antihypertensive treatment was carried out using the Lebanese Medication Adherence Scale-14 (LMAS-14), consisting of 14 items. Data were collected before therapy (T1), 3 months (T2), 6 months (T3) and 12 months (T4) followed the first dose. Adherence was assessed on 101 patients in the CG group and 165 respondents in the IG group.
In the period T1 in both groups CG and IG, a moderate adherence to treatment was recorded with indices equal to 35.9 ± 1.2 and 35.9 ± 1.3, respectively (p ≤ 0.05). A decrease in adherence in the CG group was determined after 3 months (35.9 ± 1.2) (p ≤ 0.05) and six months later (36.5 ± 3.2) in comparison with relatively high adherence among respondents in the IG group in periods T2 (39.5 ± 1.2) and T3 (40.5 ± 1.2) (p ≤ 0.001). After 12 months (T4) on the adherence scale in patients who used the mobile application "MyTherapy" (IG), despite a slight decrease in scores, the results were relatively higher (40.3 ± 1.3) compared with the CG group (33.6 ± 1.9) (p ≤ 0.001).
The analysis of adherence of patients with primary health care in Almaty (Kazakhstan) with chronic arterial hypertension showed the effectiveness of using the 'MyTherapy' mobile application in increasing patient adherence. The obtained data on the positive effect of the use of digital technologies require further research to assess the possibility of wider implementation in healthcare.
中亚地区尚未对确诊高血压患者的治疗依从性水平进行评估。这包括缺乏关于数字技术对高血压管理影响的信息。
本研究旨在评估使用移动应用程序对确诊动脉高血压患者治疗依从性的影响。
在哈萨克斯坦阿拉木图的门诊对517例确诊动脉高血压患者进行了一项多中心随机对照研究。患者被随机分为干预组(IG)和对照组(CG)。IG组患者使用一款移动应用程序,该程序可以创建个性化的服药时间表,包括视觉和音频提醒。使用由14个项目组成的黎巴嫩药物治疗依从性量表-14(LMAS-14)评估抗高血压治疗的依从性。在首次服药后的治疗前(T1)、3个月(T2)、6个月(T3)和12个月(T4)收集数据。对CG组的101例患者和IG组的165例受访者进行了依从性评估。
在T1期,CG组和IG组的治疗依从性均为中等,指数分别为35.9±1.2和35.9±1.3(p≤0.05)。与IG组受访者在T2期(39.5±1.2)和T3期(40.5±1.2)的较高依从性相比,CG组在3个月后(35.9±1.2)(p≤0.05)和6个月后(36.5±3.2)的依从性有所下降(p≤0.001)。在使用移动应用程序“MyTherapy”(IG)的患者中,12个月后(T4),尽管得分略有下降,但结果仍比CG组(33.6±1.9)相对更高(40.3±1.3)(p≤0.001)。
对哈萨克斯坦阿拉木图初级卫生保健机构中慢性动脉高血压患者的依从性分析表明,使用“MyTherapy”移动应用程序可有效提高患者的依从性。关于使用数字技术产生积极效果的现有数据需要进一步研究,以评估在医疗保健领域更广泛应用的可能性。