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一名免疫功能正常的患者在冠状动脉搭桥手术后由[具体病因未给出]引起的胸骨骨髓炎。

Sternal osteomyelitis caused by in an immunocompetent patient following coronary artery bypass surgery.

作者信息

Nwaedozie Somto, Mojarrab Javad Najjar, Gopinath Prathima, Fritsche Thomas, Nasser Rana M

机构信息

Department of Internal Medicine, Marshfield Clinic Health System - Marshfield, Marshfield, WI 54449, USA.

Department of Pathology, Marshfield Clinic Health System - Marshfield, Marshfield, WI 54449, USA.

出版信息

IDCases. 2022 Jun 23;29:e01548. doi: 10.1016/j.idcr.2022.e01548. eCollection 2022.

DOI:10.1016/j.idcr.2022.e01548
PMID:35801008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9253898/
Abstract

Skin commensals, especially gram-positive cocci, are the usual microbial organisms that cause post-operative sternal wound infections. Rarely, environmental bacteria such as spp. have been implicated as etiological agents in post-cardiac procedure surgical site infections. We report a case of a patient who presented with post-coronary artery bypass sternal osteomyelitis caused by this uncommon pathogen, and review relevant medical literature to identify commonalities in presentation, diagnosis and management. Repeat isolation of in the setting of post-procedure wound infection should raise suspicion for a real pathogenicity. Definitive identification requires a broad range of bacterial PCR DNA amplification and sequencing followed by susceptibility testing as treatment may require a prolonged course of antibiotics.

摘要

皮肤共生菌,尤其是革兰氏阳性球菌,是导致术后胸骨伤口感染的常见微生物。很少有环境细菌如某些菌种被认为是心脏手术后手术部位感染的病原体。我们报告了一例由这种罕见病原体引起的冠状动脉搭桥术后胸骨骨髓炎患者,并回顾相关医学文献以确定其临床表现、诊断和管理方面的共性。在术后伤口感染的情况下反复分离出该菌应引起对其真正致病性的怀疑。明确鉴定需要进行广泛的细菌PCR DNA扩增和测序,随后进行药敏试验,因为治疗可能需要长时间使用抗生素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/79baedeee56d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/a6b85381ec18/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/b132d51b54a2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/fa6674ed0752/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/cfcca199bebd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/79baedeee56d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/a6b85381ec18/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/b132d51b54a2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/fa6674ed0752/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/cfcca199bebd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd2/9253898/79baedeee56d/gr5.jpg

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本文引用的文献

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Sternal osteomyelitis by in an immunocompetent patient after open heart surgery.免疫功能正常的患者在心脏直视手术后发生胸骨骨髓炎。 (原句“by in”表述有误,推测可能是“by...”,这里按修正后翻译,若原文无误请告知)
Ann Card Anaesth. 2019 Apr-Jun;22(2):221-224. doi: 10.4103/aca.ACA_125_18.
2
sternal wound infection treated with ceftaroline: case report and literature review.用头孢洛林治疗胸骨伤口感染:病例报告及文献综述
JMM Case Rep. 2017 Sep 13;4(9):e005113. doi: 10.1099/jmmcr.0.005113. eCollection 2017 Sep.
3
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JMM Case Rep. 2016 Oct 31;3(5):e005067. doi: 10.1099/jmmcr.0.005067. eCollection 2016 Oct.
4
Gordonia: isolation and identification in clinical samples and role in biotechnology.戈登氏菌属:临床样本中的分离与鉴定及其在生物技术中的作用
Folia Microbiol (Praha). 2017 May;62(3):245-252. doi: 10.1007/s12223-017-0491-1. Epub 2017 Jan 20.
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Sternal wound infection after cardiac surgery: incidence and risk factors according to clinical presentation.心脏手术后胸骨伤口感染:根据临床表现的发生率和危险因素。
Clin Microbiol Infect. 2015 Jul;21(7):674.e11-8. doi: 10.1016/j.cmi.2015.03.025. Epub 2015 Apr 14.
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