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由……引起的胸骨伤口感染:通过基质辅助激光解吸电离飞行时间质谱法鉴定

Sternal wound infection caused by : identification by MALDI-TOF MS.

作者信息

Rodriguez-Lozano Jesús, Pérez-Llantada Enrique, Agüero Jesús, Rodríguez-Fernández Ana, Ruiz de Alegria Carlos, Martinez-Martinez Luis, Calvo Jorge

机构信息

Marqués de Valdecilla University Hospital, Santander , Cantabria , Spain.

出版信息

JMM Case Rep. 2016 Oct 31;3(5):e005067. doi: 10.1099/jmmcr.0.005067. eCollection 2016 Oct.

Abstract

INTRODUCTION

spp. infections are uncommon. However, a few clinical cases have been reported in the literature, particularly those involving immunocompromised hosts. Advanced microbiology diagnosis techniques, such as matrix-assisted laser desorption ionization-time of flight MS (MALDI-TOF MS), have been recently introduced in clinical microbiology laboratories in order to improve microbial identification, resulting in better patient management.

CASE PRESENTATION

Here, we present a new clinical case of persistent wound infection caused by in a 64-year-old woman after a mitral valve replacement, using two MALDI-TOF-based systems for identifying this micro-organism.

CONCLUSION

Both MALDI-TOF systems were able to identify spp.; thus, providing a useful tool that overcomes the current limitations of phenotypic identification associated with this micro-organism. Although the technique validation deserves additional verification, our study provides guidance about MALDI-TOF as a fast and easy method for spp. identification.

摘要

引言

[特定菌种名称]感染并不常见。然而,文献中已报道了一些临床病例,特别是那些涉及免疫功能低下宿主的病例。为了改善微生物鉴定,从而实现更好的患者管理,诸如基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)等先进的微生物诊断技术最近已被引入临床微生物实验室。

病例介绍

在此,我们报告一例64岁女性在二尖瓣置换术后由[特定菌种名称]引起的持续性伤口感染的新临床病例,使用了两种基于MALDI-TOF的系统来鉴定这种微生物。

结论

两种MALDI-TOF系统均能够鉴定[特定菌种名称];因此,提供了一种有用的工具,克服了与该微生物相关的当前表型鉴定的局限性。尽管该技术的验证值得进一步核实,但我们的研究为MALDI-TOF作为一种快速简便的[特定菌种名称]鉴定方法提供了指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598f/5343147/7c404b7065b8/jmmcr-03-5067-f001.jpg

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