Ambesh Paurush, Kapoor Aditya, Kazmi Danish H, Elsheshtawy Moustafa, Shetty Vijay, Lin Yu S, Kamholz Stephan
Department of Internal Medicine, Maimonides Medical Center, New York City, USA.
Department of Cardiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Ann Card Anaesth. 2019 Apr-Jun;22(2):221-224. doi: 10.4103/aca.ACA_125_18.
Gordonia is a catalase-positive, aerobic, nocardioform, Gram-positive staining actinomycete that also shows weak acid-fast staining. Several Gordonia species are commonly found in the soil. The bacterium has been isolated from the saliva of domesticated/wild dogs as well. In hospitalized patients, most commonly it is found in the setting of intravascular catheter-related infections. However, recent reports show that it is being increasingly isolated from sternal wounds, skin/neoplastic specimens and from pleural effusions. Gordonia shares many common characteristics with Rhodococcus and Nocardia. Ergo, it is commonly misrecognized as Nocardia or Rhodococcus. Since this pathogen requires comprehensive morphological and biochemical testing, it is often difficult and cumbersome to isolate the species. Broad-range Polymerase Chain Reaction (PCR) and sequencing with genes like 16S rRNA or hsp65 are used to correctly identify the species. Identification is essential for choosing and narrowing the right antimicrobial agent. Herein, we report our experience with a patient who presented with sternal osteomyelitis after infection with this elusive bug.
戈登氏菌属是一种过氧化氢酶阳性、需氧、诺卡氏菌样、革兰氏阳性染色的放线菌，也显示弱阳性抗酸染色。几种戈登氏菌属菌种常见于土壤中。这种细菌也从家养/野生狗的唾液中分离出来。在住院患者中，最常见于血管内导管相关感染的情况。然而，最近的报告显示，它越来越多地从胸骨伤口、皮肤/肿瘤标本和胸腔积液中分离出来。戈登氏菌属与红球菌属和诺卡氏菌属有许多共同特征。因此，它常被误认作诺卡氏菌属或红球菌属。由于这种病原体需要全面的形态学和生化检测，分离该菌种往往困难且繁琐。广泛聚合酶链反应（PCR）以及使用16S rRNA或hsp65等基因进行测序可用于正确鉴定该菌种。鉴定对于选择和缩小合适的抗菌药物范围至关重要。在此，我们报告我们对一名感染这种难以捉摸的病菌后出现胸骨骨髓炎患者的治疗经验。
