Raible L H, Gorzalka B B
Behav Neurosci. 1987 Apr;101(2):215-8. doi: 10.1037//0735-7044.101.2.215.
The present experiment examined the effects of a single neonatal injection of 1 mg or 100 micrograms of testosterone propionate (TP) on the sexual behavior and morphology of the female Mongolian gerbil. Four groups were created: vehicle-treated males (VM), 1-mg TP-treated females (HTP), 100-micrograms TP-treated females (LTP), and vehicle-treated females (VF). In adulthood, tests of sexual behavior were carried out after gonadectomy and appropriate hormone replacement therapy. Results indicated that LTP, HTP, and VM animals were significantly less receptive than VF animals. In addition, VM animals displayed significantly more male sexual activity than HTP, LTP, or VF animals. Immediately after the final test for male sexual behavior, subjects were weighed, anogenital distances recorded, and scent glands measured (length and width). Results indicated that a significant degree of morphological masculinization had occurred in HTP subjects for all measures and for LTP subjects for scent gland width and anogenital distance. These findings suggest that in the gerbil, significant morphological masculinization and behavioral defeminization can both occur in teh absence of significant behavioral masculinization.
本实验研究了新生期单次注射1毫克或100微克丙酸睾酮（TP）对雌性蒙古沙鼠性行为和形态的影响。实验设立了四组：接受溶剂处理的雄性（VM）、接受1毫克TP处理的雌性（HTP）、接受100微克TP处理的雌性（LTP）以及接受溶剂处理的雌性（VF）。成年后，在性腺切除及适当的激素替代治疗后进行性行为测试。结果表明，LTP、HTP和VM组动物的接受性显著低于VF组动物。此外，VM组动物表现出的雄性性行为显著多于HTP、LTP或VF组动物。在最后一次雄性性行为测试后，立即对实验对象称重，记录肛门与生殖器之间的距离，并测量气味腺（长度和宽度）。结果表明，对于所有测量指标，HTP组实验对象均出现了显著程度的形态男性化，而LTP组实验对象在气味腺宽度和肛门与生殖器之间的距离方面出现了形态男性化。这些研究结果表明，在沙鼠中，即使没有明显的行为雄性化，也可能出现显著的形态男性化和行为去雌性化。
