Northcote R J, Cooke M B
Br Heart J. 1987 Apr;57(4):319-28. doi: 10.1136/hrt.57.4.319.
The feasibility of using the cold pressor test and the sustained isometric handgrip test as alternatives to dynamic exercise for stressing the heart was investigated. Serial changes in heart rate, blood pressure, and left ventricular performance induced by these tests were studied by radionuclide ventriculography in patients with coronary artery disease and in normal volunteers. Both tests significantly increased heart rate and blood pressure. The reproducibility of serial evaluation of ejection fraction response to cold pressor and isometric handgrip stresses was satisfactory but the sensitivity for detecting coronary artery disease was not. Both stress tests are valuable interventions for the serial evaluation of left ventricular function by radionuclide ventriculography, but they should not be used to detect coronary artery disease.
研究了使用冷加压试验和持续等长握力试验替代动态运动来对心脏施加压力的可行性。通过放射性核素心室造影术,研究了冠心病患者和正常志愿者在这些试验中引起的心率、血压和左心室功能的系列变化。两种试验均显著提高了心率和血压。冷加压和等长握力应激时射血分数反应的系列评估的可重复性令人满意,但检测冠心病的敏感性则不然。两种应激试验都是通过放射性核素心室造影术对左心室功能进行系列评估的有价值的干预措施,但不应将它们用于检测冠心病。