Munich University of Applied Sciences HM, Department of Computer Science and Mathematics, Germany.
Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States of America.
Biomed Phys Eng Express. 2022 Jul 19;8(5). doi: 10.1088/2057-1976/ac7fbc.
In this paper we propose and investigate a new detector with multiple strip detector arrays (SDA) for monitoring MLC shaped x-ray beams for radiotherapy treatment.Each SDA measures 1D dose profiles equivalent to dose projections. The goal of such a detector is to determine individual MLC leaf positions as well as the Monitor Units (MU) per MLC segment during radiotherapy. In the present work we investigate an optimal SDA detector configuration and reconstruction algorithm. We determine the accuracy of SDA for different treatment sites (spine, pelvis, retroperitoneum, prostate, brain SRT, SRS, lung and head and neck). We perform a simulation study accounting for different type of MLC leaf positional errors: random MLC leaf, systematic for the whole leaf bank and systematic for an individual leaf. In a similar fashion, we also account for errors in Monitor Units per segment.We demonstrate that for a broad range of IMRT treatment plans a robust reconstruction of errors is achievable with only 3 projections (3 sets of SDA oriented at at 0°, 45° and 135°). The SDA is capable of capturing both systematic errors in leaf banks and individual leaves as well as random errors sufficient for practical clinical purposes.These features of the SDA detector makes it suitable for real-time Quality Control of MLC collimated linac output.
在本文中,我们提出并研究了一种新的探测器,该探测器具有多个条带探测器阵列(SDA),用于监测用于放射治疗的 MLC 形状的 X 射线束。每个 SDA 测量相当于剂量投影的一维剂量分布。这种探测器的目的是确定单个 MLC 叶片位置以及每个 MLC 段的监视器单位(MU)。在目前的工作中,我们研究了一种最佳的 SDA 探测器配置和重建算法。我们确定了 SDA 在不同治疗部位(脊柱、骨盆、后腹膜、前列腺、脑 SRT、SRS、肺和头颈部)的准确性。我们进行了一项模拟研究,考虑了不同类型的 MLC 叶片位置误差:随机 MLC 叶片、整个叶片库的系统误差和单个叶片的系统误差。同样,我们还考虑了每个段的监视器单位的误差。我们证明,对于广泛的调强放射治疗计划,仅使用 3 个投影(3 组以 0°、45°和 135°定向的 SDA)即可实现对误差的稳健重建。SDA 能够捕获叶片库和单个叶片中的系统误差以及足以满足实际临床目的的随机误差。SDA 探测器的这些特性使其适用于 MLC 准直直线加速器输出的实时质量控制。