Wulandari Ika O, Pebriatin Baiq E, Valiana Vita, Hadisaputra Saprizal, Ananto Agus D, Sabarudin Akhmad
Chemistry Department, Faculty of Mathematics and Natural Science, Universitas Brawijaya, Malang 65145, Indonesia.
Educational Chemistry Department, Faculty of Teacher Training and Education, University of Mataram, Mataram 83125, Indonesia.
Materials (Basel). 2022 Jul 1;15(13):4641. doi: 10.3390/ma15134641.
The synthesis of silver nanoparticles using plant extracts, widely known as a green synthesis method, has been extensively studied. Nanoparticles produced through this method have applications as antibacterial agents. Bacterial and viral infection can be prevented by use of antibacterial agents such as soap, disinfectants, and hand sanitizer. Silver nanoparticles represent promising hand sanitizer ingredients due to their antibacterial activity and can enable reduced use of alcohol and triclosan. This study employed silver nanoparticles synthesized using banana peel extract ( L.). Nanoparticle effectiveness as a hand sanitizer can be enhanced by coating with a biocompatible polymer such as chitosan. The characterization of silver nanoparticles was conducted using UV-Vis, with an obtained peak at 434.5 nm. SEM-EDX analysis indicated nanoparticles with a spherical morphology. Silver nanoparticles coated with chitosan were characterized through FTIR to verify the attached functional groups. Gel hand sanitizers were produced using silver nanoparticles coated with different chitosan concentrations. Several tests were undertaken to determine the gel characteristics, including pH, syneresis, and antibacterial activity. Syneresis leads to unstable gels, but was found to be inhibited by adding chitosan at a concentration of 2%. Antibacterial activity was found to increase with increase in chitosan concentration.
利用植物提取物合成银纳米颗粒，这一广为人知的绿色合成方法已得到广泛研究。通过这种方法生产的纳米颗粒可作为抗菌剂使用。使用肥皂、消毒剂和洗手液等抗菌剂可以预防细菌和病毒感染。由于银纳米颗粒具有抗菌活性，它们是很有前景的洗手液成分，并且可以减少酒精和三氯生的使用。本研究采用了用香蕉皮提取物（L.）合成的银纳米颗粒。通过用壳聚糖等生物相容性聚合物进行包覆，可以提高纳米颗粒作为洗手液的有效性。使用紫外可见光谱对银纳米颗粒进行表征，在434.5nm处获得一个峰值。扫描电子显微镜-能谱分析表明纳米颗粒呈球形形态。通过傅里叶变换红外光谱对包覆壳聚糖的银纳米颗粒进行表征，以验证附着的官能团。使用包覆有不同壳聚糖浓度的银纳米颗粒制备了凝胶洗手液。进行了多项测试以确定凝胶的特性，包括pH值、脱水收缩和抗菌活性。脱水收缩会导致凝胶不稳定，但发现添加2%浓度的壳聚糖可抑制脱水收缩。抗菌活性随壳聚糖浓度的增加而增加。
