Grove Kristen, Edgar Dale W, Chih HuiJun, Harrold Meg, Natarajan Varsha, Mohd Sheeraz, Hurn Elizabeth, Cavalheri Vinicius
Department of Physiotherapy, Royal Perth Hospital, Royal Perth Bentley Group, East Metropolitan Health Service, Perth, WA 6000, Australia.
Department of Physiotherapy, Fiona Stanley Hospital, South Metropolitan Health Service, Murdoch, WA 6150, Australia.
J Clin Med. 2022 Jun 22;11(13):3602. doi: 10.3390/jcm11133602.
↔This study aims to compare the characteristics, in-hospital data and rehabilitation needs between those who tested positive versus negative for COVID-19 during hospitalisation with suspected COVID-19. In this cross-sectional study, a convenience sample of adults admitted to Western Australian tertiary hospitals with suspected COVID-19 was recruited. Participants were grouped according to their polymerase chain reaction (PCR) test result into COVID-19 positive (COVID+) and COVID-19 negative (COVID−) groups. Between-group comparisons of characteristics of the participants and hospital admission data were performed. Sixty-five participants were included (38 COVID+ and 27 COVID−; 36 females [55%]). Participants in the COVID+ group had greater acute hospital length of stay (LOS) (median [25−75th percentile] 10 [5−21] vs. 3 [2−5] days; p < 0.05] and only those with COVID+ required mechanical ventilation (8 [21%] participants). Twenty-one percent of the COVID+ participants were discharged to inpatient rehabilitation (7% of the COVID− participants). Of note, pre-existing pulmonary disease was more prevalent in the COVID− group (59% vs. 13%; p < 0.05). Within the COVID+ group, when compared to participants discharged home, those who required inpatient rehabilitation had worse peripheral oxygen saturation (SpO2) on admission (86 ± 5.7% vs. 93 ± 3.8%; p < 0.05) and longer median LOS (30 [23−37] vs. 7 [4−13] days; p < 0.05). Despite having less people with pre-existing pulmonary disease, the COVID+ group required more care and rehabilitation than the COVID− group. In the COVID+ group, SpO2 on hospital presentation was associated with LOS, critical care needs, mechanical ventilation duration and the need for inpatient rehabilitation.
本研究旨在比较住院期间新冠病毒检测呈阳性与阴性的疑似新冠病毒感染患者之间的特征、住院数据及康复需求。在这项横断面研究中，选取了西澳大利亚三级医院收治的疑似新冠病毒感染的成年患者作为便利样本。参与者根据其聚合酶链反应（PCR）检测结果分为新冠病毒阳性（COVID+）组和新冠病毒阴性（COVID−）组。对参与者的特征及住院数据进行组间比较。共纳入65名参与者（38名COVID+和27名COVID−；36名女性[55%]）。COVID+组的急性住院时长（LOS）更长（中位数[第25 - 75百分位数]为10[5 - 21]天，而COVID−组为3[2 - 5]天；p < 0.05），且只有COVID+组的患者需要机械通气（8名[21%]参与者）。21%的COVID+参与者出院后进入住院康复（COVID−参与者为7%）。值得注意的是，既往肺部疾病在COVID−组更为普遍（59%对13%；p < 0.05）。在COVID+组中，与出院回家的参与者相比，需要住院康复的参与者入院时外周血氧饱和度（SpO2）更低（86 ± 5.7%对93 ± 3.8%；p < 0.05），且中位LOS更长（30[23 - 37]天对7[4 - 13]天；p < 0.05）。尽管既往肺部疾病患者较少，但COVID+组比COVID−组需要更多的护理和康复。在COVID+组中，入院时的SpO2与LOS、重症监护需求、机械通气时长及住院康复需求相关。
