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肌肉无力、功能能力和 COVID-19 ICU 幸存者的恢复。

Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors.

机构信息

Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France.

Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France.

出版信息

BMC Anesthesiol. 2021 Mar 2;21(1):64. doi: 10.1186/s12871-021-01274-0.

Abstract

BACKGROUND

Few studies have evaluated muscle strength in COVID-19 ICU survivors. We aimed to report the incidence of limb and respiratory muscle weakness in COVID-19 ICU survivors.

METHOD

We performed a cross sectional study in two ICU tertiary Hospital Settings. COVID-19 ICU survivors were screened and respiratory and limb muscle strength were measured at the time of extubation. An ICU mobility scale was performed at ICU discharge and walking capacity was self-evaluated by patients 30 days after weaning from mechanical ventilation.

RESULTS

Twenty-three patients were included. Sixteen (69%) had limb muscle weakness and 6 (26%) had overlap limb and respiratory muscle weakness. Amount of physiotherapy was not associated with muscle strength. 44% of patients with limb weakness were unable to walk 100 m 30 days after weaning.

CONCLUSION

The large majority of COVID-19 ICU survivors developed ICU acquired limb muscle weakness. 44% of patients with limb weakness still had severely limited function one-month post weaning.

摘要

背景

鲜有研究评估 COVID-19 重症监护室幸存者的肌肉力量。我们旨在报告 COVID-19 重症监护室幸存者的四肢和呼吸肌无力的发生率。

方法

在两家 ICU 三级医院进行了一项横断面研究。对 COVID-19 重症监护室幸存者进行了筛选,并在拔管时测量了呼吸肌和四肢肌肉力量。在 ICU 出院时进行了 ICU 活动能力量表评估,患者在机械通气脱机后 30 天自我评估行走能力。

结果

共纳入 23 名患者。16 名(69%)存在四肢肌肉无力,6 名(26%)存在四肢和呼吸肌重叠无力。物理治疗的次数与肌肉力量无关。四肢无力的患者中有 44%在脱机后 30 天无法行走 100 米。

结论

大多数 COVID-19 重症监护室幸存者发生了 ICU 获得性四肢肌肉无力。四肢无力的患者中有 44%在脱机后一个月仍存在严重的功能受限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03d6/7923467/c0413da05838/12871_2021_1274_Fig1_HTML.jpg

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