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J Orthop Surg Res. 2021 Nov 24;16(1):690. doi: 10.1186/s13018-021-02830-7.
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Diabetes and treatment with orally administrated corticosteroids negatively affect treatment outcome at follow-up after acute Achilles tendon rupture.糖尿病和口服皮质类固醇治疗会对急性跟腱断裂后随访时的治疗结果产生负面影响。
Knee Surg Sports Traumatol Arthrosc. 2021 May;29(5):1584-1592. doi: 10.1007/s00167-020-06371-0. Epub 2020 Nov 19.
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Obesity Increases the Risk of Tendinopathy, Tendon Tear and Rupture, and Postoperative Complications: A Systematic Review of Clinical Studies.肥胖增加了发生腱病、肌腱撕裂和断裂以及术后并发症的风险:临床研究的系统评价。
Clin Orthop Relat Res. 2020 Aug;478(8):1839-1847. doi: 10.1097/CORR.0000000000001261.
6
Post-operative MRI and US appearance of the Achilles tendons.跟腱术后的 MRI 和超声表现。
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Elevated lipid levels in patients with achilles tendon ruptures: a retrospective matching study.跟腱断裂患者的血脂水平升高:一项回顾性匹配研究。
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Delayed (14-30 Days) Percutaneous Repair of Achilles Tendon Ruptures Offers Equally Good Results As Compared With Acute Repair.延迟(14-30 天)经皮修复跟腱断裂与急性修复相比具有同样良好的效果。
Am J Sports Med. 2020 Apr;48(5):1181-1188. doi: 10.1177/0363546520908592. Epub 2020 Mar 16.
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Plaster cast versus functional brace for non-surgical treatment of Achilles tendon rupture (UKSTAR): a multicentre randomised controlled trial and economic evaluation.石膏固定与功能性支具治疗非手术治疗跟腱断裂的比较(UKSTAR):一项多中心随机对照试验和经济评价。
Lancet. 2020 Feb 8;395(10222):441-448. doi: 10.1016/S0140-6736(19)32942-3.
10
Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing.2 型糖尿病对肌腱稳态和愈合的影响。
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跟腱断裂与代谢紊乱性疾病:一项多中心流行病学研究

Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study.

作者信息

Oliva Francesco, Marsilio Emanuela, Asparago Giovanni, Giai Via Alessio, Biz Carlo, Padulo Johnny, Spoliti Marco, Foti Calogero, Oliva Gabriella, Mannarini Stefania, Rossi Alessandro Alberto, Ruggieri Pietro, Maffulli Nicola

机构信息

Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.

Department of Orthopaedic Surgery and Traumatology, San Camillo-Forlanini Hospital, 00152 Rome, Italy.

出版信息

J Clin Med. 2022 Jun 27;11(13):3698. doi: 10.3390/jcm11133698.

DOI:10.3390/jcm11133698
PMID:35806982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9267833/
Abstract

Achilles tendon ruptures are common. Metabolic disorders, such as diabetes mellitus, hypercholesterolemia, thyroid disorders, and obesity, impair tendons health, leading to Achilles tendinopathy and likely predisposing patients to Achilles tendon ruptures. Patients who visited the Orthopedic Outpatient Clinics and the Accident and Emergency Departments of five different hospitals in Italy were recruited. Through telephone interviews, we administered a questionnaire to all the patients who had undergone surgical ATR repair, evaluating their past medical history, sport- and work-related activities, drug use, and post-operative rehabilitation outcomes. "Return to work activities/sport" was negatively predicted by the presence of a metabolic disorder (β = -0.451; OR = 0.637) and 'open' surgery technique (β = -0.389; OR = 0.678). "Medical complications" were significantly predicted by metabolic disorders (β = 0.600 (0.198); OR = 1.822) and was negatively related to 'mini-invasive' surgery (i.e., not 'open' nor 'percutaneous') (β = -0.621; OR = 0.537). "Immediate weightbearing" and "immediate walking without assistance" were negatively predicted by 'open' technique (β = -0.691; OR = 0.501 and β = -0.359 (0.174; OR = 0.698)). Metabolic conditions can strongly affect post-operative outcomes following surgical repair of acute Achilles tendon tears.

摘要

跟腱断裂很常见。代谢紊乱,如糖尿病、高胆固醇血症、甲状腺疾病和肥胖,会损害肌腱健康,导致跟腱病,并可能使患者易患跟腱断裂。我们招募了在意大利五家不同医院的骨科门诊和急诊就诊的患者。通过电话访谈,我们向所有接受过手术修复急性跟腱断裂的患者发放了问卷,评估他们的既往病史、与运动和工作相关的活动、药物使用情况以及术后康复结果。代谢紊乱(β = -0.451;OR = 0.637)和“开放”手术技术(β = -0.389;OR = 0.678)对“恢复工作活动/运动”有负面预测作用。代谢紊乱(β = 0.600(0.198);OR = 1.822)对“医疗并发症”有显著预测作用,且与“微创”手术(即非“开放”也非“经皮”)呈负相关(β = -0.621;OR = 0.537)。“立即负重”和“立即独立行走”受到“开放”技术的负面预测(β = -0.691;OR = 0.501和β = -0.359(0.174;OR = 0.698))。代谢状况会强烈影响急性跟腱断裂手术修复后的术后结果。