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缺血性中风患者药物治疗信念的相关因素

Factors Related to Beliefs about Medication in Ischemic Stroke Patients.

作者信息

Kim Gye-Gyoung, Yoo Sung-Hee, Park Man-Seok, Park Hyun-Young, Cha Jae-Kwan

机构信息

College of Nursing, Chonnam National University, Gwangju 61469, Korea.

Department of Neurology, Chonnam National University Hospital, Gwangju 61469, Korea.

出版信息

J Clin Med. 2022 Jul 1;11(13):3825. doi: 10.3390/jcm11133825.

DOI:10.3390/jcm11133825
PMID:35807119
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9267671/
Abstract

Background: Medication beliefs are known as predictors of medication adherence. However, understanding of the relevance of these beliefs is lacking. Therefore, this study aimed to identify medication beliefs, and their influencing factors, in stroke survivors. Methods: This was a secondary analysis, using baseline data from a longitudinal study conducted to predict long-term medication adherence in Korean stroke survivors, and included 471 patients. Medication beliefs were investigated using the Belief about Medicine Questionnaire (BMQ), and the belief score and attitudes were derived from the “necessity” and “concern” scores, which are subscales of the BMQ. Multiple linear regression was used to determine independent factors influencing medication beliefs. Results: The mean score of medication beliefs is 7.07 ± 6.32, and the accepting group comprises 288 patients (61.1%). Medication beliefs are significantly higher in older adults (p < 0.001), females (p = 0.001), and patients with non-type D personality (p = 0.023), low-state anxiety (p < 0.001), high stroke severity (p = 0.001), a high number of medications (p < 0.001), and high knowledge about medications (p = 0.001). Conclusion: This study shows that type D personality, state anxiety, and knowledge about medication are major mediating factors for improving medication beliefs. These results may help healthcare professionals develop strategies to enhance medication adherence, by improving patients’ medication beliefs.

摘要

背景

药物信念被认为是药物依从性的预测指标。然而,对这些信念的相关性缺乏了解。因此,本研究旨在确定中风幸存者的药物信念及其影响因素。方法:这是一项二次分析,使用了一项纵向研究的基线数据,该研究旨在预测韩国中风幸存者的长期药物依从性,纳入了471名患者。使用药物信念问卷(BMQ)调查药物信念,信念得分和态度来自BMQ的子量表“必要性”和“担忧”得分。采用多元线性回归确定影响药物信念的独立因素。结果:药物信念的平均得分为7.07±6.32,接受组包括288名患者(61.1%)。老年人(p<0.001)、女性(p=0.001)、非D型人格患者(p=0.023)、低状态焦虑患者(p<0.001)、高卒中严重程度患者(p=0.001)、用药数量多的患者(p<0.001)以及药物知识丰富的患者(p=0.001)的药物信念显著更高。结论:本研究表明,D型人格、状态焦虑和药物知识是改善药物信念的主要中介因素。这些结果可能有助于医护人员通过改善患者的药物信念来制定提高药物依从性的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e8a/9267671/aafd5567839d/jcm-11-03825-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e8a/9267671/aafd5567839d/jcm-11-03825-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e8a/9267671/aafd5567839d/jcm-11-03825-g001a.jpg

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本文引用的文献

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J Neurosci Nurs. 2022 Feb 1;54(1):35-41. doi: 10.1097/JNN.0000000000000621.
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Factors Associated with Medication Beliefs in Patients with Parkinson's Disease: A Cross-Sectional Study.帕金森病患者用药信念的相关因素:一项横断面研究。
J Mov Disord. 2021 May;14(2):133-143. doi: 10.14802/jmd.20147. Epub 2021 May 3.
3
Factors Influencing 1-Year Medication Adherence of Korean Ischemic Stroke Survivors.
影响韩国缺血性脑卒中幸存者 1 年药物依从性的因素。
Int J Behav Med. 2020 Apr;27(2):225-234. doi: 10.1007/s12529-020-09854-z.
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Post-stroke medication adherence and persistence rates: a meta-analysis of observational studies.卒中后药物治疗依从性和持续性率:观察性研究的荟萃分析。
J Neurol. 2021 Jun;268(6):2090-2098. doi: 10.1007/s00415-019-09660-y. Epub 2019 Dec 2.
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Executive Summary of Stroke Statistics in Korea 2018: A Report from the Epidemiology Research Council of the Korean Stroke Society.《2018年韩国卒中统计执行摘要:来自韩国卒中协会流行病学研究委员会的报告》
J Stroke. 2019 Jan;21(1):42-59. doi: 10.5853/jos.2018.03125. Epub 2018 Dec 18.
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Oncol Nurs Forum. 2018 Jul 2;45(4):508-526. doi: 10.1188/18.ONF.508-526.
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Diseases Linked to Polypharmacy in Elderly Patients.老年患者多重用药相关疾病
Curr Gerontol Geriatr Res. 2017;2017:4276047. doi: 10.1155/2017/4276047. Epub 2017 Dec 25.
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It's all a matter of necessity and concern: A structural equation model of adherence to antihypertensive medication.这完全是一个必要性和关注的问题:抗高血压药物治疗依从性的结构方程模型。
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