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调查匈牙利成年糖尿病患者对药物治疗的态度及自我管理的障碍:一项横断面研究。

Investigating attitudes towards medication and barriers to self-management among Hungarian adults with diabetes mellitus: A cross-sectional study.

作者信息

Bíró Klára, Varga Mihály, Dombrádi Viktor, Kovács Nóra, Nagy Attila, Bányai Gábor, Boruzs Klára

机构信息

Institute of Health Economics and Management, Faculty of Economics and Business, University of Debrecen, Debrecen, Hungary.

Doctoral School of Health Sciences, University of Debrecen, Debrecen, Hungary.

出版信息

PLoS One. 2025 Mar 26;20(3):e0317034. doi: 10.1371/journal.pone.0317034. eCollection 2025.

Abstract

The key to effective patient care is the patient's proper cooperation, so it is important to examine the beliefs about medicine and self-management among diabetes patients. Therefore, the primary aim of the study was to investigate the attitude toward metformin medication and self-management of adult patients with diabetes in Hungary. A total of 591 metformin-taking diabetes patients completed the Beliefs about Medicine Questionnaire, while 283 metformin-taking diabetes patients completed the Environmental Barrier Assessment Scale. Multivariate regression analysis was conducted to investigate which socio-demographic factors influence the beliefs regarding medicines and various environmental barriers to diabetes self-management. Participants who reported a good or very good financial status were more likely to feel the need to take metformin compared to those perceiving bad or very bad financial status (coef = 0.25; p = 0.020). Respondents between 55-64 years and those older than 65 were significantly less concerned about metformin than those aged 18-24 years (coef = -0.47; p = 0.028 and coef = -0.41; p = 0.047). Participants with secondary education were significantly less likely to think that metformin was harmful than those with primary education (coef = -0.50; p = 0.009). In addition, those aged 35 or older saw more barriers to taking medication than those aged 18-24 years (35-44: coef = -0.54; p = 0.020; 45-54: coef = -1.15; p < 0.001; 55-64: coef = -1.06; p < 0.001; 65 years or older: coef = -1.48; p < 0.001). Also, significant negative association was found for several factors (such as age, education, self-reported financial status, subjective health status) with barriers regarding exercise. Overall, socio-demographic factors significantly impact both the attitude toward medicine and diabetes self-management. However, the impact considerably varies according to different beliefs and environmental barriers. To further improve drug adherence and self-management for diabetes, doctors should take into consideration the relevant socio-demographic factors when communicating with their patients.

摘要

有效患者护理的关键在于患者的适当配合,因此,研究糖尿病患者对药物治疗和自我管理的看法很重要。因此,本研究的主要目的是调查匈牙利成年糖尿病患者对二甲双胍药物治疗和自我管理的态度。共有591名服用二甲双胍的糖尿病患者完成了《药物信念问卷》,而283名服用二甲双胍的糖尿病患者完成了《环境障碍评估量表》。进行多变量回归分析,以调查哪些社会人口统计学因素会影响对药物的信念以及糖尿病自我管理的各种环境障碍。报告财务状况良好或非常好的参与者比那些认为财务状况差或非常差的参与者更有可能觉得有必要服用二甲双胍(系数=0.25;p=0.020)。55至64岁的受访者和65岁以上的受访者对二甲双胍的担忧明显低于18至24岁的受访者(系数=-0.47;p=0.028和系数=-0.41;p=0.047)。接受中等教育的参与者认为二甲双胍有害的可能性明显低于接受小学教育的参与者(系数=-0.50;p=0.009)。此外,35岁及以上的人比18至24岁的人看到更多服药障碍(35至44岁:系数=-0.54;p=0.020;45至54岁:系数=-1.15;p<0.001;55至64岁:系数=-1.06;p<0.001;65岁及以上:系数=-1.48;p<0.001)。此外,还发现几个因素(如年龄、教育程度、自我报告的财务状况、主观健康状况)与运动障碍存在显著负相关。总体而言,社会人口统计学因素对药物治疗态度和糖尿病自我管理均有显著影响。然而,根据不同的信念和环境障碍,影响程度差异很大。为了进一步提高糖尿病患者的药物依从性和自我管理能力,医生在与患者沟通时应考虑相关的社会人口统计学因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7cb/11940427/153c5affecfb/pone.0317034.g001.jpg

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