Navarro-Martos Remedios, Nieto-Escamez Francisco
Departamento de Psicología, Universidad de Almería, Carretera del Sacramento S/N, 04120 Almería, Spain.
Centro de Evaluación y Rehabilitación Neuropsicológica (CERNEP), Universidad de Almería, Carretera del Sacramento S/N, 04120 Almería, Spain.
J Clin Med. 2022 Jul 5;11(13):3907. doi: 10.3390/jcm11133907.
(1) Background: Alzheimer's disease is an irreversible brain disease, and current treatments are aimed at fighting cognitive decline. We have explored the feasibility of a game-based intervention for people with moderate Alzheimer's disease; (2) Methods: Six participants, five women and one man, were recruited from a day center to participate in a five-week study, which included a re- and post-evaluation with the Montreal Cognitive Assessment (MoCA) and INECO Frontal Screening (IFS) tests. Three participants were assigned to the control group and three others to the experimental one. Both groups performed a play activity consisting of assembling a pie toy. Participants in the experimental group were asked to make a pie matching a sample after a time interval. Control group participants were asked to freely assemble a pie without the matching component; (3) Results: Patients were shown to be motivated during such an activity during the nine sessions. The experimental group showed a significant increase in IFS scores when comparing the post- and pre-intervention assessments. No significant differences were observed in MoCA scores; (4) The intervention created a social and emotional climate suitable to maintaining participants' satisfaction and motivation, as well as to developing executive function while promoting positive emotions.
(1) 背景：阿尔茨海默病是一种不可逆的脑部疾病，目前的治疗旨在对抗认知衰退。我们探讨了针对中度阿尔茨海默病患者进行基于游戏的干预的可行性；(2) 方法：从日间护理中心招募了6名参与者，5名女性和1名男性，参与一项为期五周的研究，该研究包括使用蒙特利尔认知评估量表（MoCA）和INECO额叶筛查量表（IFS）进行重新评估和干预后评估。3名参与者被分配到对照组，另外3名被分配到实验组。两组都进行了一项由组装拼图玩具组成的游戏活动。实验组的参与者在一段时间间隔后被要求制作一个与样本匹配的拼图。对照组的参与者被要求自由组装一个没有匹配组件的拼图；(3) 结果：在九次活动期间，患者在此类活动中表现出积极性。在比较干预后和干预前的评估时，实验组的IFS分数显著提高。MoCA分数未观察到显著差异；(4) 该干预营造了一种适合维持参与者满意度和积极性的社会和情感氛围，同时在促进积极情绪的同时发展执行功能。
