Bullock N, Thurston A V
Br J Urol. 1987 Apr;59(4):340-2. doi: 10.1111/j.1464-410x.1987.tb04645.x.
Tetracycline (Achromycin, Lederle) solution was used to produce sclerosis of 37 hydroceles and 18 epididymal cysts in patients over the age of 50 years. All but one of the epididymal cysts were sclerosed satisfactorily at 9 months; 35 hydroceles sclerosed satisfactorily, although four patients required re-treatment at 3 months. One patient required orchiectomy for an infected haematocele. Pain after instillation of tetracycline was an occasional complication which could be prevented by prophylactic spermatic cord block. Tetracycline sclerotherapy is a safe and effective alternative to surgery for hydroceles and epididymal cysts in older patients.
使用四环素（金霉素，莱德利公司生产）溶液对50岁以上患者的37例鞘膜积液和18例附睾囊肿进行硬化治疗。除1例附睾囊肿外，其余所有囊肿在9个月时均成功硬化；35例鞘膜积液硬化效果良好，不过有4例患者在3个月时需要再次治疗。1例患者因感染性血囊肿需要进行睾丸切除术。四环素注入后疼痛是偶尔出现的并发症，可通过预防性精索阻滞来预防。对于老年患者的鞘膜积液和附睾囊肿，四环素硬化疗法是一种安全有效的手术替代方法。
