Kovačević Ana, Vidatić Ines, Škorić Iva, Valent Morić Bernardica
Department of Pediatrics, Sestre Milosrdnice University Hospital Center, Vinogradska cesta 29, 10000, Zagreb, Croatia.
Pediatr Cardiol. 2023 Mar;44(3):599-606. doi: 10.1007/s00246-022-02963-4. Epub 2022 Jul 9.
The aim of our study was to investigate the influence of the degree of obesity on ambulatory blood pressure parameters in selected group of office normotensive obese children and adolescents. Our study involved 119 obese patients (55 males, 46.2%) aged 7-18 years divided into 3 groups based on their body mass index Z-score, who underwent ambulatory blood pressure monitoring. Our results show that obese patients, even when office normotensive, have alterations in blood pressure values obtained by ambulatory blood pressure monitoring. We found a positive correlation between systolic and diastolic blood pressure and body mass index in our patients (p [Formula: see text] 0.001). Daytime blood pressure load correlated with rising body mass index and was higher in groups II and III compared to group I (p < 0.001). Body mass index category did not influence the dipping pattern in our subjects although most of our subjects (66.4%) showed non-dipping pattern for systolic blood pressure. The difference in blood pressure variability was confirmed only for daytime systolic and diastolic values between groups I and II (p = 0.019 and p = 0.002, respectively). In conclusion, our study showed that in office normotensive obese children and adolescents, systolic and diastolic blood pressure values obtained by ambulatory blood pressure monitoring are higher in subjects with higher body mass index. Patients with increased body mass index also have higher percentage of blood pressure readings above 95 percentile and increased daytime blood pressure variability. Obese patients show non-dipping pattern, independently of the rising body mass index category.
我们研究的目的是调查肥胖程度对选定的办公室血压正常的肥胖儿童和青少年动态血压参数的影响。我们的研究纳入了119名7至18岁的肥胖患者（55名男性，占46.2%），根据他们的体重指数Z评分分为3组，并进行了动态血压监测。我们的结果表明，肥胖患者即使办公室血压正常，通过动态血压监测获得的血压值也有改变。我们发现患者的收缩压和舒张压与体重指数之间呈正相关（p [公式：见正文] 0.001）。日间血压负荷与体重指数的升高相关，与I组相比，II组和III组更高（p < 0.001）。体重指数类别并未影响我们研究对象的血压波动模式，尽管我们的大多数研究对象（66.4%）收缩压呈现非勺型模式。仅在I组和II组之间，日间收缩压和舒张压的血压变异性差异得到证实（分别为p = 0.019和p = 0.002）。总之，我们的研究表明，在办公室血压正常的肥胖儿童和青少年中，体重指数较高的受试者通过动态血压监测获得的收缩压和舒张压值更高。体重指数增加的患者血压读数高于第95百分位数的百分比也更高，且日间血压变异性增加。肥胖患者呈现非勺型模式，与体重指数类别升高无关。
