Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt O'Brien Center for Kidney Disease, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
J Am Geriatr Soc. 2022 Aug;70(8):2219-2224. doi: 10.1111/jgs.17942. Epub 2022 Jul 9.
Chronic kidney disease (CKD) is prevalent and burdensome among older adults in the United States. CKD affects at least 15% of the US population, and adults over 65 comprise the largest subset within this group. In this special article, we highlight key findings of three recent original investigations in nephrology and describe each study, relevance to the care of older adults, and current areas of uncertainty that warrant further investigation. Articles relate to removal of the race adjustment in the estimation of kidney function, the use of novel therapeutics to halt CKD progression and improve cardiovascular outcomes, and medication management for short-term pain control in CKD.
慢性肾脏病（CKD）在美国老年人中普遍存在且负担沉重。CKD 至少影响了美国 15%的人口，而 65 岁以上的成年人是这一人群中最大的一部分。在这篇特别文章中，我们重点介绍了肾脏病学最近三项原始研究的主要发现，并描述了每一项研究与老年患者护理的相关性，以及目前需要进一步研究的不确定性领域。这些文章涉及到在估计肾功能时去除种族调整、使用新型治疗方法来阻止 CKD 进展和改善心血管结局，以及 CKD 短期疼痛控制的药物管理。
