Research Fellow Statistician, The Procter and Gamble Company, Mason, Ohio.
Principal Investigator, All Sum Research Center Ltd., Mississauga, Ontario, Canada.
Compend Contin Educ Dent. 2022 Mar;43(3):f20-f29.
This study compared the gingivitis and plaque reduction efficacy of a novel smart-connected oscillating-rotating (O-R) electric toothbrush with micro-vibrations, used in Sensitive mode with an extra gentle ("sensitive") brush head, to the efficacy of a soft manual toothbrush.
This was a 12-week, examiner-blind, two-treatment, parallel-group clinical trial with 100 adult subjects (N = 100) having evidence of gingivitis and plaque at baseline. Subjects were randomly assigned to use either the O-R electric rechargeable toothbrush (Oral-B iO with Oral-B Gentle Care brush head) or the soft manual toothbrush (Oral-B Indicator). Gingivitis was assessed with the modified gingival index (MGI) and the gingival bleeding index (GBI). Plaque was assessed with the Rustogi modification of the navy plaque index (RMNPI). Patients were classified as having a "healthy" or "not healthy" gingival case status according to the criteria of the American Academy of Periodontology and the European Federation of Periodontology. Efficacy assessments and oral soft-tissue examinations were conducted before brushing at baseline, week 1, and week 12. The baseline assessment included both pre- and post-brushing plaque evaluations to evaluate single-use plaque removal efficacy.
All 100 subjects completed the trial. Subjects had a mean age of 49.1 years; 72% were females. The O-R brush group had a significantly higher percentage of subjects who transitioned from "not healthy" to "healthy" gingival case status than did the manual brush group. Plaque reduction for the O-R brush group was also significantly greater (P ≤ .009) than for the manual brush group for whole mouth, gingival margin, and interproximal region, from day 1 (single use) through 12 weeks. Both brushes were well tolerated.
The novel O-R toothbrush with micro-vibrations used in Sensitive mode with an extra gentle brush head provided significantly greater gingivitis and plaque reduction than did a manual toothbrush over 12 weeks.
本研究比较了一种新型智能连接的振荡-旋转（O-R）电动牙刷与微振动在敏感模式下的洁牙和菌斑减少效果，该牙刷使用了超软（“敏感”）刷头，与软毛手动牙刷的效果进行比较。
这是一项为期 12 周、 examiner-blind、 两治疗、平行组临床试验，共有 100 名成年受试者（N = 100）在基线时有牙龈炎和菌斑的证据。受试者被随机分配使用 O-R 电动可充电牙刷（Oral-B iO 与 Oral-B Gentle Care 刷头）或软毛手动牙刷（Oral-B Indicator）。牙龈炎采用改良的牙龈指数（MGI）和牙龈出血指数（GBI）进行评估。菌斑采用海军菌斑指数（RMNPI）的 Rustogi 改良法进行评估。根据美国牙周病学会和欧洲牙周病学会的标准，将患者分为“健康”或“不健康”的牙龈病例状态。在基线、第 1 周和第 12 周进行疗效评估和口腔软组织检查。基线评估包括刷牙前和刷牙后的单次菌斑评估，以评估单次使用的菌斑去除效果。
所有 100 名受试者均完成了试验。受试者的平均年龄为 49.1 岁；72%为女性。O-R 牙刷组有更高比例的受试者从“不健康”转变为“健康”的牙龈病例状态，而手动牙刷组则没有。与手动牙刷组相比，O-R 牙刷组的菌斑减少量也显著更大（P ≤.009），无论是全口、牙龈边缘还是邻间区域，从第 1 天（单次使用）到第 12 周都是如此。两种牙刷都有很好的耐受性。
在敏感模式下使用超软（“敏感”）刷头的新型 O-R 振动牙刷在 12 周内提供了比手动牙刷更显著的牙龈炎和菌斑减少效果。
