用于哺乳动物糖科学研究的工具。
Tools for mammalian glycoscience research.
机构信息
Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Department of Microbiology and Immunology, Scripps Research, La Jolla, CA 92037, USA.
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
出版信息
Cell. 2022 Jul 21;185(15):2657-2677. doi: 10.1016/j.cell.2022.06.016. Epub 2022 Jul 8.
Abstract
Cellular carbohydrates or glycans are critical mediators of biological function. Their remarkably diverse structures and varied activities present exciting opportunities for understanding many areas of biology. In this primer, we discuss key methods and recent breakthrough technologies for identifying, monitoring, and manipulating glycans in mammalian systems.
摘要
细胞碳水化合物或糖是生物功能的关键介质。它们结构的显著多样性和不同的活性为理解生物学的许多领域提供了令人兴奋的机会。在这个入门中，我们讨论了在哺乳动物系统中鉴定、监测和操纵聚糖的关键方法和最新突破技术。
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