Departamento de Medicina Interna, Facultad de Medicina y Farmacia, Universidad de Tay-Nguyen, Buon Ma Thuot, Viet Nam.
Departamento de Medicina Interna, Universidad de Medicina y Farmacia, Ciudad de Ho Chi Minh, Ho Chi Minh, Viet Nam; Departamento de Gastroenterología, Hospital de Nhan Dan Gia Dinh, Ho Chi Minh, Viet Nam.
Rev Gastroenterol Mex (Engl Ed). 2023 Oct-Dec;88(4):341-346. doi: 10.1016/j.rgmxen.2022.06.012. Epub 2022 Jul 7.
The prevalence of gastroesophageal reflux disease (GERD) has been reported to be increasing in recent years. However, there have been few reports on the prevalence of GERD during pregnancy in the Asian population. The aim of our study was to evaluate the prevalence and characteristics of GERD in Vietnamese pregnant women.
This cross-sectional study was conducted at the antenatal clinic of the Nhan Dan Gia Dinh Hospital, Ho Chi Minh, Vietnam. Four hundred females, at various stages of pregnancy, were enrolled. GERD was diagnosed if there was troublesome heartburn and/or acid regurgitation, at least once a week, during the current pregnancy.
The overall prevalence of GERD in pregnancy was 38.5% (154/400). The prevalence of GERD in the third trimester was significantly higher than that in the second trimester (46.8% vs. 30.7%, P=0.008) and tended to be higher than its prevalence in the first trimester (46.8% vs. 35.4%, P=0.051). In the pregnant women with GERD, the frequency of regurgitation was significantly higher than that of heartburn (92.9% vs. 30.5%, P<0.001). Those typical symptoms were more prevalent in the daytime, compared with nighttime.
Our study showed that GERD was prevalent during pregnancy in Vietnam. In the pregnant women with GERD, regurgitation was much more common than heartburn, and those typical reflux symptoms occurred more frequently in the daytime, compared with nighttime.
近年来，胃食管反流病（GERD）的患病率有所增加。然而，亚洲人群妊娠期 GERD 的患病率鲜有报道。本研究旨在评估越南孕妇 GERD 的患病率和特点。
这是一项横断面研究，在越南胡志明市的 Nhan Dan Gia Dinh 医院的产前诊所进行。共纳入 400 名处于不同妊娠阶段的女性。如果在当前妊娠期间每周至少出现一次烧心和/或酸反流，则诊断为 GERD。
妊娠期间 GERD 的总体患病率为 38.5%（154/400）。第三孕期 GERD 的患病率明显高于第二孕期（46.8% vs. 30.7%，P=0.008），且有高于第一孕期的趋势（46.8% vs. 35.4%，P=0.051）。在患有 GERD 的孕妇中，反流的频率明显高于烧心（92.9% vs. 30.5%，P<0.001）。这些典型症状在白天比夜间更为常见。
本研究表明，GERD 在越南妊娠期间很常见。在患有 GERD 的孕妇中，反流比烧心更为常见，且这些典型的反流症状在白天比夜间更为常见。
