Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Department of Cardiology, Chonnam National University Medical School, Gwangju, Korea.
Korean J Intern Med. 2022 Jul;37(4):777-785. doi: 10.3904/kjim.2021.427. Epub 2022 Jun 28.
BACKGROUND/AIMS: Recurrent acute myocardial infarction (AMI) is an adverse cardiac event in patients with a first AMI. The predictors of recurrent AMI after the first AMI in patients who underwent successful percutaneous coronary intervention (PCI) have not been elucidated.
We analyzed the data collected from 9,869 patients (63.2 ± 12.4 years, men:women = 7,446:2,423) who were enrolled in the Korea Acute Myocardial Infarction Registry-National Institute of Health between November 2011 and October 2015, had suffered their first AMI and had received successful PCI during the index hospitalization. Multivariable logistic regression analysis was performed to identify the independent predictors of recurrent AMI following the first AMI.
The cumulative incidence of recurrent AMI after successful PCI was 3.6% (359/9,869). According to the multivariable logistic regression analysis, the significant predictive factors for recurrent AMI were diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.
In this Korean prospective cohort study, the independent predictors of recurrent AMI after successful PCI for the first AMI were diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.
背景/目的：复发性急性心肌梗死（AMI）是首次发生 AMI 患者的一种不良心脏事件。对于接受经皮冠状动脉介入治疗（PCI）成功的患者，首次 AMI 后发生复发性 AMI 的预测因素尚未阐明。
我们分析了 2011 年 11 月至 2015 年 10 月期间在韩国急性心肌梗死注册-国立卫生研究院登记的 9869 例患者（63.2±12.4 岁，男性：女性=7446:2423）的数据，这些患者首次发生 AMI 并在住院期间接受了成功的 PCI。采用多变量逻辑回归分析来确定首次 AMI 后复发性 AMI 的独立预测因素。
成功 PCI 后复发性 AMI 的累积发生率为 3.6%（359/9869）。根据多变量逻辑回归分析，复发性 AMI 的显著预测因素为糖尿病、肾功能不全、非典型胸痛和多血管疾病。
在这项韩国前瞻性队列研究中，首次 AMI 后成功 PCI 治疗复发性 AMI 的独立预测因素为糖尿病、肾功能不全、非典型胸痛和多血管疾病。
