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结缔组织发育异常对出牙影响的研究。

Research of connective tissue dysplasia influence on teething.

作者信息

Korshunov Andrey, Vagner Vladimir, Konev Vladimir, Moskovskiy Sergey, Kuryatnikov Kirill, Skurikhina Anna, Yakovlev Vladislav, Nurakhmetova Adel

机构信息

Department of Dentistry, Omsk State Medical University, Omsk, Russian Federation.

Department of the Organization of the Dental Service, Licensing and Accreditation, Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russian Federation.

出版信息

Saudi Dent J. 2022 Jul;34(5):385-389. doi: 10.1016/j.sdentj.2022.05.002. Epub 2022 May 11.

DOI:10.1016/j.sdentj.2022.05.002
PMID:35814839
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9263759/
Abstract

PURPOSE

This work aimed to study the rate and quality of maturation of the mineral component of retained teeth 3.8, 4.8 and lower jaw fragment of a human in connective tissue dysplasia in different periods of postpartum ontogenesis.

METHODS

The study involved 102 men (76 with connective tissue dysplasia and 26 without connective tissue dysplasia) divided into groups by age: 31-40, 41-50, 51-60 years. One tooth 3.8, 4.8 and a fragment of the alveolar part of the lower jaw in the projection of teeth 3.8, 4.8 0.5*0.5 cm in size were extracted from each examinee for medical indications.

RESULTS

Low optical density values are observed at the age of 41-50 years, at the age of 51-60 years, indicating decreased mineral density and the presence of total areas of hypomineralization from the age 31-40 years in connective tissue dysplasia. At the age of 41-50, 51-60 years, at the boundary of connective tissue structures and periosteum, a pronounced sclerosis and deformation of delineation elements were observed; at the age of 31-40 years, the indicated changes were less pronounced. At the age of 31-40 years, the level of bone plate dissection has a local character, after 40 years, it has a generalized character.

CONCLUSION

Progressive osteoporosis of the mandible and incomplete amelogenesis are an obstacle to the correct and harmonious teething of the lower wisdom teeth after the age of 30.

摘要

目的

本研究旨在探讨产后个体发育不同阶段结缔组织发育异常患者中,保留牙3.8、4.8及下颌骨片段矿物质成分的成熟速率和质量。

方法

研究纳入102名男性(76名结缔组织发育异常患者和26名无结缔组织发育异常患者),按年龄分为31 - 40岁、41 - 50岁、51 - 60岁三组。因医学指征,从每位受试者口中拔除一颗3.8、4.8牙以及下颌骨在3.8、4.8牙投影处大小为0.5×0.5 cm的牙槽骨片段。

结果

在41 - 50岁、51 - 60岁时观察到低光学密度值,表明矿物质密度降低,且在结缔组织发育异常患者中,从31 - 40岁起就存在矿化不足的总面积。在41 - 50岁、51 - 60岁时,在结缔组织结构与骨膜边界处,观察到轮廓元素明显硬化和变形;在31 - 40岁时,上述变化不太明显。在31 - 40岁时,骨板分离水平具有局部特征,40岁以后则具有全身性特征。

结论

下颌骨进行性骨质疏松和釉质形成不完全是30岁以后下颌智齿正常萌出和协调萌出的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c3e/9263759/3cd7605579d5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c3e/9263759/dfe0ee25ef58/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c3e/9263759/3cd7605579d5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c3e/9263759/dfe0ee25ef58/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c3e/9263759/3cd7605579d5/gr2.jpg

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2
Deformation behavior of normal human enamel: A study by nanoindentation.正常人类牙釉质的变形行为:一项通过纳米压痕进行的研究。
J Mech Behav Biomed Mater. 2020 Aug;108:103799. doi: 10.1016/j.jmbbm.2020.103799. Epub 2020 Apr 19.
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Variation in the timing of enamel formation in modern human deciduous canines.
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Arch Oral Biol. 2020 Jun;114:104719. doi: 10.1016/j.archoralbio.2020.104719. Epub 2020 Apr 19.
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The geometrical structure of interfaces in dental enamel: A FIB-STEM investigation.牙釉质界面的几何结构:FIB-STEM 的研究。
Acta Biomater. 2020 Mar 1;104:17-27. doi: 10.1016/j.actbio.2019.12.040. Epub 2020 Jan 7.
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Application of Image Compression Ratio Analysis as a Method for Quantifying Complexity of Dental Enamel Microstructure.图像压缩比分析在量化牙釉质微观结构复杂性中的应用。
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