Department of Dentistry, Omsk State Medical University, Omsk, Russia.
Biochemistry Research Laboratory, Omsk State Pedagogical University, Omsk, Russia.
Indian J Dent Res. 2024 Apr 1;35(2):164-169. doi: 10.4103/ijdr.ijdr_600_23. Epub 2024 Sep 14.
This study aimed to investigate the rate and quality of maturation of the mineral component of impacted teeth 38 and 48 and a fragment of the human lower jaw with connective tissue dysplasia (CTD) in different periods of postnatal ontogenesis.
The study involved 102 males (76 with CTD and 26 without CTD), divided into age groups: 31-40, 41-50 and 51-60 years. For medical reasons, teeth 38 and 48 were removed from each patient, as well as a fragment of the alveolar part of the lower jaw in the projection of teeth 38 and 48 measuring 0.5 × 0.5 cm. The odontological parameters, the mineral density of the enamel and the lower jaw, the length and width of the enamel prisms, the spatial organisation of collagen fibrils and the dimensions of the bone plates of the lower jaw were determined.
A decrease in optical density was observed at the age of 41-50 and 51-60 years with dysplasia, which indicated a decrease in mineral density and the presence of total areas of hypomineralisation relative to the age of 31-40 years. In the age groups of 41-50 and 51-60 years, pronounced sclerosis and deformation of the delimiting elements were observed at the border of the connective tissue structures and the periosteum. At the age of 31-40 years, the level of stratification of the bone plates was local; after 40 years, it was generalised.
Progressive osteoporosis of the lower jaw and incomplete amelogenesis are obstacles to the correct and harmonious eruption of the lower 'wisdom' teeth after 30 years.
本研究旨在探讨不同出生后发育阶段，38 号和 48 号阻生牙以及伴结缔组织发育不良（CTD）的人类下颌骨组织碎片中矿物质成分的成熟率和成熟质量。
本研究纳入了 102 名男性（76 名伴 CTD，26 名不伴 CTD），分为 31-40 岁、41-50 岁和 51-60 岁三个年龄组。由于医疗原因，每位患者均拔除了 38 号和 48 号牙齿，以及 38 号和 48 号牙齿牙槽部分的 0.5×0.5cm 组织碎片。测量了牙齿的牙科学参数、牙釉质和下颌骨的矿物质密度、牙釉质棱柱的长度和宽度、胶原纤维的空间组织以及下颌骨骨板的尺寸。
伴 CTD 患者在 41-50 岁和 51-60 岁时观察到光密度降低，这表明与 31-40 岁相比，矿物质密度降低且存在总面积的低矿化。在 41-50 岁和 51-60 岁年龄组中，在结缔组织结构和骨膜的边界处观察到明显的硬化和限定元素变形。在 31-40 岁年龄组中，骨板的分层水平为局部；40 岁后，为全身性。
下颌骨进行性骨质疏松症和不完全釉质发生是 30 岁后下颌“智慧”牙正确和协调萌出的障碍。
