Tan Liang-Zhang, Tian Fang, Chen Lu, Sun Li-Na, Gong Xue, Liang Jing-Li, Zhang Hong, Li Xiao-Rong
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China.
Int J Ophthalmol. 2022 Jun 18;15(6):932-939. doi: 10.18240/ijo.2022.06.10. eCollection 2022.
To assess the changes in the peripapillary vasculature and macular thickness after cataract surgery using two phacoemulsification systems with optical coherence tomography angiography (OCTA).
Fifty-two eyes of 52 patients with age-related cataract were randomized into two groups for phacoemulsification: Infiniti group (26 patients) using the Infiniti phacoemulsification system with gravity-fluidics and Centurion group (26 patients) using the Centurion phacoemulsification system with active-fluidics. The peripapillary vessel density (PVD) and macular thickness were examined using OCTA at baseline and at 1d, 1 and 3mo after cataract surgery.
In the Infiniti group, the PVD was significantly reduced at 1d after the cataract surgery (<0.001). However, the retinal nerve fiber layer (RNFL) thickness showed no significant change during the follow-up. Change in PVD 1d postoperatively was significantly negatively correlated to the cumulative dissipated energy (CDE), estimated fluid usage (EFU), effective phacoemulsification time (EPT), intraocular pressure (IOP), and total operating time (TOT; <0.05). The macular thickness was significantly increased in all regions after the cataract surgery (<0.05). However, no significant changes were found in the macular vessel density (VD) during the follow-up (>0.05). In the Centurion group, the VD and thickness in the optic papilla and macula did not significantly change in all regions during the follow-up (all >0.05). The best-corrected visual acuity (BCVA) significantly improved in both groups postoperatively (<0.001).
Using the Infiniti phacoemulsification system, OCTA provides a promising analysis of retinal vascular alterations, demonstrating a reduction of the PVD and an increase in the macular thickness. The Centurion phacoemulsification system can provide better retinal vasculature preservation during cataract surgery.
使用光学相干断层扫描血管造影（OCTA）评估两种超声乳化系统白内障手术后视乳头周围血管系统和黄斑厚度的变化。
将52例年龄相关性白内障患者的52只眼随机分为两组进行超声乳化手术：使用具有重力流体系统的Infiniti超声乳化系统的Infiniti组（26例患者）和使用具有主动流体系统的Centurion超声乳化系统的Centurion组（26例患者）。在基线以及白内障手术后1天、1个月和3个月时使用OCTA检查视乳头周围血管密度（PVD）和黄斑厚度。
在Infiniti组中，白内障手术后1天时PVD显著降低（<0.001）。然而，在随访期间视网膜神经纤维层（RNFL）厚度无显著变化。术后1天PVD的变化与累积消散能量（CDE）、估计液体用量（EFU）、有效超声乳化时间（EPT）、眼压（IOP）和总手术时间（TOT；<0.05）显著负相关。白内障手术后所有区域的黄斑厚度均显著增加（<0.05）。然而，在随访期间黄斑血管密度（VD）无显著变化（>0.05）。在Centurion组中，随访期间视乳头和黄斑的VD和厚度在所有区域均无显著变化（均>0.05）。两组术后最佳矫正视力（BCVA）均显著提高（<0.001）。
使用Infiniti超声乳化系统，OCTA对视网膜血管改变提供了有前景的分析，显示PVD降低和黄斑厚度增加。Centurion超声乳化系统在白内障手术期间可提供更好的视网膜血管系统保护。
