Rambelli Chiara, Mazzoli Davide, Galletti Martina, Basini Giacomo, Zerbinati Paolo, Prati Paolo, Mascioli Francesca, Masiero Stefano, Merlo Andrea
Gait & Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Department of Neuroscience, Section of Rehabilitation, University of Padova, Padua, Italy.
Front Hum Neurosci. 2022 Jun 24;16:914340. doi: 10.3389/fnhum.2022.914340. eCollection 2022.
Charcot-Marie-Tooth disease (CMT) is a slow and progressive peripheral motor sensory neuropathy frequently associated with the cavo-varus foot deformity. We conducted a scoping review on the clinical scales used to assess foot deviations in CMT patients and analyzed their metric properties.
A first search was conducted to retrieve all scales used to assess foot characteristics in CMT patients from the Medline, Web of Science, Google Scholar, Cochrane, and PEDro databases. A second search was conducted to include all studies that evaluated the metric properties of such identified scales from the same databases. We followed the methodologic guidelines specific for scoping reviews and used the PICO framework to set the eligibility criteria. Two independent investigators screened all papers.
The first search found 724 papers. Of these, 41 were included, using six different scales: "Foot Posture Index" (FPI), "Foot Function Index", "Maryland Foot Score", "American Orthopedic Foot & Ankle Society's Hindfoot Evaluation Scale", "Foot Health Status Questionnaire", Wicart-Seringe grade. The second search produced 259 papers. Of these, 49 regarding the metric properties of these scales were included. We presented and analyzed the properties of all identified scales in terms of developmental history, clinical characteristics (domains, items, scores), metric characteristics (uni-dimensionality, inter- and intra-rater reliability, concurrent validity, responsiveness), and operational characteristics (normative values, manual availability, learning time and assessors' characteristics).
Our results suggested the adoption of the six-item version of the FPI scale (FPI-6) for foot assessment in the CMT population, with scoring provided by Rasch Analysis. This scale has demonstrated high applicability in different cohorts after a short training period for clinicians, along with good psychometric properties. FPI-6 can help health professionals to assess foot deformity in CMT patients over the years.
夏科-马里-图思病（CMT）是一种缓慢进展的周围运动感觉神经病变，常伴有足内翻畸形。我们对用于评估CMT患者足部偏差的临床量表进行了一项范围综述，并分析了它们的计量特性。
首先进行检索，从Medline、科学网、谷歌学术、Cochrane和PEDro数据库中获取所有用于评估CMT患者足部特征的量表。第二次检索纳入所有评估这些已识别量表计量特性的研究，这些研究来自相同数据库。我们遵循范围综述的特定方法学指南，并使用PICO框架设定纳入标准。两名独立研究人员筛选所有论文。
首次检索找到724篇论文。其中，41篇被纳入，使用了六种不同量表：“足部姿势指数”（FPI）、“足部功能指数”、“马里兰足部评分”、“美国矫形足踝协会后足评估量表”、“足部健康状况问卷”、维卡特-塞林格分级。第二次检索产生259篇论文。其中，49篇关于这些量表计量特性的论文被纳入。我们从发展历史、临床特征（领域、条目、评分）、计量特征（单维度性、评分者间和评分者内信度、同时效度、反应度）以及操作特征（标准值、手册可用性、学习时间和评估者特征）方面展示并分析了所有已识别量表的特性。
我们的结果表明，在CMT人群中进行足部评估时应采用FPI量表的六项版本（FPI-6），并通过拉施分析进行评分。该量表在临床医生经过短时间培训后，已在不同队列中显示出高适用性，同时具有良好的心理测量特性。多年来，FPI-6可帮助卫生专业人员评估CMT患者的足部畸形。
