Department of Oral and Maxillofacial Surgery, Jamia Millia Islamia Central University, New Delhi, India.
Department of Electrical Engineering, Faculty of Engineering and Technology, Jamia Millia Islamia Central University, New Delhi, India.
J Med Life. 2022 May;15(5):698-704. doi: 10.25122/jml-2021-0240.
Temporomandibular joint disorders (TMDs) are ailments affecting the jaws and allied structures, resulting in many pathologies (TMJ hypermobility, internal disc derangement, bone changes, degenerative disorders, and ankylosis). Pain, clicking or crepitus, restricted range of motion, deranged jaw function, and deflected or deviated mouth opening and closing are the commonly observed manifestations in TMDs. Internal derangement refers to an aberrant relation of the articular disc to the condyle and fossa, respectively. Conventional therapies highlight the role of non-invasive conservative treatment strategies, namely joint unloading, anti-inflammatory drugs, and physiotherapy. Current literature has emphasized the use of corticosteroids and platelet-rich plasma (PRP) as treatment strategies in TMDs. This study aimed to evaluate whether intra-articular injection of PRP after normal saline lavage in TMJ minimizes the symptoms of TMDs, as compared to injection of normal saline. Thirty patients with TMD according to research diagnostic criteria (RDC) were selected. One group received arthrocentesis with normal saline, and the other group received arthrocentesis with PRP injection. The patients were assessed for pain, maximum inter-incisal mouth opening, bite force, and TMJ sounds. TMDs treated by PRP injection had slightly better results. More studies are required to substantiate the outcome. Injections of PRP were more effective in reducing the symptoms than arthrocentesis with normal saline.
颞下颌关节紊乱病（TMD）是影响颌骨和相关结构的疾病，导致许多病理学改变（TMJ 过度活动、关节盘前移位、骨改变、退行性疾病和关节强直）。疼痛、弹响或摩擦音、运动范围受限、下颌功能紊乱以及开口和闭口时的偏斜或偏移是 TMD 的常见表现。关节盘内移位是指关节盘相对于髁突和关节窝的异常关系。传统疗法强调非侵入性保守治疗策略的作用，即关节减压、抗炎药物和物理疗法。目前的文献强调了在 TMD 中使用皮质类固醇和富含血小板的血浆（PRP）作为治疗策略。本研究旨在评估与生理盐水冲洗后的关节内注射生理盐水相比，TMJ 内注射 PRP 是否可以最大程度地减轻 TMD 的症状。根据研究诊断标准（RDC）选择了 30 名 TMD 患者。一组接受生理盐水关节穿刺术，另一组接受 PRP 注射关节穿刺术。评估患者的疼痛、最大开口度、咬合力和 TMJ 声音。PRP 注射治疗的 TMD 结果稍好。需要更多的研究来证实结果。与生理盐水关节穿刺术相比，PRP 注射在减轻症状方面更有效。
