Salzano Giovanni, Maffia Francesco, Dell'Aversana Orabona Giovanni
Department of Neurosciences, Maxillofacial Surgery Unit, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy.
J Basic Clin Physiol Pharmacol. 2025 May 22;36(2-3):237-240. doi: 10.1515/jbcpp-2025-0042. eCollection 2025 Mar 1.
This manuscript reviews advancements in oral and maxillofacial surgery, encompassing minimally invasive techniques, innovations in implant dentistry, regenerative medicine, innovations in temporomandibular joint, and novel methodologies in salivary gland surgery.
A comprehensive analysis of recent developments in the field is presented, focusing on the integration of new technologies and biological therapies. Emphasis is placed on minimally invasive procedures, virtual surgical planning with CAD/CAM and 3D printing, implant design and placement innovations, and regenerative approaches.
Minimally invasive procedures, often employing endoscopic or robotic assistance, reduce surgical morbidity and accelerate patient recovery. Virtual surgical planning and 3D printing enhance pre-surgical accuracy. Innovations in implant design, surface modification, and guided surgery improve prosthetic outcomes. Regenerative medicine and tissue engineering, including the use of growth factors and stem cells, offer new options for tissue restoration. In temporomandibular joint disorders, these strategies aim to improve function and reduce reliance on arthroplasty. The use of superficial dermal substitutes in salivary gland surgery reduces complications such as Frey syndrome.
These advancements reflect a paradigm shift in oral and maxillofacial surgery, enhancing patient care and expanding the field's potential through precision, biologically based therapies, and less invasive approaches.
本文回顾口腔颌面外科的进展，包括微创技术、种植牙创新、再生医学、颞下颌关节创新以及唾液腺手术的新方法。
对该领域近期的发展进行全面分析，重点关注新技术与生物疗法的整合。着重介绍了微创手术、CAD/CAM虚拟手术规划和3D打印、种植体设计与植入创新以及再生方法。
微创手术通常借助内镜或机器人辅助，降低手术发病率并加速患者康复。虚拟手术规划和3D打印提高了术前准确性。种植体设计、表面改性和引导手术方面的创新改善了修复效果。再生医学和组织工程，包括生长因子和干细胞的应用，为组织修复提供了新选择。在颞下颌关节紊乱症中，这些策略旨在改善功能并减少对关节成形术的依赖。唾液腺手术中使用浅表真皮替代物可减少诸如味觉出汗综合征等并发症。
这些进展反映了口腔颌面外科的范式转变，通过精准、基于生物学的疗法和侵入性较小的方法，提升了患者护理水平并拓展了该领域的潜力。
