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关节腔内注射富血小板血浆治疗颞下颌关节紊乱病及其与关节腔穿刺术的比较

Intra-articular platelet-rich plasma injection for the treatment of temporomandibular disorders and a comparison with arthrocentesis.

作者信息

Hancı Mustafa, Karamese Mehtap, Tosun Zekeriya, Aktan Tahsin Murad, Duman Selcuk, Savaci Nedim

机构信息

Istanbul Medipol University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Istanbul, Turkey.

Selcuk University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Alaaddin Keykubat Kampüsü, Selçuklu, Konya, Turkey.

出版信息

J Craniomaxillofac Surg. 2015 Jan;43(1):162-6. doi: 10.1016/j.jcms.2014.11.002. Epub 2014 Nov 15.

Abstract

BACKGROUND

Temporomandibular joint (TMJ) internal derangements are progressive painful conditions and cause joint dysfunction, joint sound, malocclusion, and locking of the mouth. Conservative and invasive techniques can be used for the treatment of TMJ internal derangements. The objective of the present study was to examine the benefit of an intra-articular platelet-rich plasma (PRP) injection and to compare this with arthrocentesis.

METHODS

Twenty patients (female: male; 15:5; age 26, 3 ± 9.3 years) for a total of 32 joints with reducible anterior disc dislocation, as confirmed by Magnetic Resonance Imaging (MRI), were divided into two groups. PRP was used for the study group, and arthrocentesis was used for the control group. Pain intensity, maximal interincisal opening, and TMJ sounds were assessed and compared for evaluation of treatment success.

RESULTS

There was a statistically significant reduction in pain intensity and joint sound and an increase in mouth opening in the study group when compared with the control group.

CONCLUSIONS

This study shows that intra-articular PRP injection for the treatment of reducible disc displacement of the TMJ is a more effective method than arthrocentesis.

摘要

背景

颞下颌关节(TMJ)内紊乱是渐进性疼痛病症,会导致关节功能障碍、关节弹响、咬合不正和张口受限。保守和侵入性技术均可用于治疗颞下颌关节内紊乱。本研究的目的是检验关节内注射富含血小板血浆(PRP)的益处,并将其与关节穿刺术进行比较。

方法

经磁共振成像(MRI)证实,20例患者(女性∶男性 = 15∶5;年龄26.3±9.3岁)共32个关节患有可复性盘前移位,被分为两组。研究组使用PRP,对照组使用关节穿刺术。评估并比较疼痛强度、最大切牙间开口度和颞下颌关节弹响,以评价治疗效果。

结果

与对照组相比,研究组的疼痛强度和关节弹响有统计学意义的降低,张口度增加。

结论

本研究表明,关节内注射PRP治疗颞下颌关节可复性盘移位比关节穿刺术更有效。

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