中医推拿加艾灸治疗退行性膝骨关节炎的疗效

Therapeutic Value of Traditional Chinese Massage plus Moxibustion for Degenerative Knee Osteoarthritis.

作者信息

Yang Jianhui, Zou Jianping, Zhang Qingfeng

机构信息

Department of Pain, First Affiliated Hospital of Xian Jiaotong University, Xi'an 710061, China.

出版信息

Evid Based Complement Alternat Med. 2022 Jun 30;2022:8305561. doi: 10.1155/2022/8305561. eCollection 2022.

DOI:10.1155/2022/8305561

PMID:35815286

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9262557/

Abstract

OBJECTIVE

To evaluate the therapeutic value of traditional Chinese massage plus moxibustion for degenerative knee osteoarthritis (DKOA).

METHODS

From January 2019 to October 2021, 152 patients with DKOA were enrolled. All patients were randomly divided into the treatment group and the control group. The control group was treated with oral glucosamine hydrochloride capsules. The treatment group was treated with traditional Chinese massage and moxibustion on the basis of the control group. The duration of treatment in the two groups was 8 weeks. The effectiveness, visual analog scale (VAS) score, the hospital for special surgery (HSS) score, World Health Organization Quality of Life Scale (WHOQOL-BREF) score, serum high-sensitivity C-reactive protein (CRP), and interleukin-6 (IL-6) levels were compared between the two groups before and after treatment.

RESULTS

There were no significant differences in age, sex, and the duration of disease between the two groups ( > 0.05). The overall response rate in the treatment group was significantly higher than that of the control group after treatment (92.1% vs 78.9%; =0.038); the VAS score of both two groups were significantly decreased, and the VAS score in the treatment group was significantly lower than that of the control group (3.5 ± 1.4 vs 4.8 ± 1.1; < 0.001); the HSS score and WHOQOL-BREF score significantly improved in both groups, and the HSS score and WHOQOL-BREF score improved more in the treatment group than those of the control group ( < 0.05). The high-sensitivity CRP level significantly decreased in both groups, and the high-sensitivity CRP level in treatment group is lower than that of the control group (2.79 ± 1.65 vs 4.37 ± 1.54; < 0.001); the IL-6 level was significantly decreased in the treatment group than in the control group (7.22 ± 3.41 vs 4.59 ± 2.98; < 0.001).

CONCLUSION

Traditional Chinese massage plus moxibustion is worthy of clinical application, which has a significant clinical effect on DKOA, reducing pain and improving knee joint function and quality of life.

摘要

目的

评估中医推拿加艾灸治疗退行性膝骨关节炎（DKOA）的疗效。

方法

选取2019年1月至2021年10月期间收治的152例DKOA患者。所有患者随机分为治疗组和对照组。对照组口服盐酸氨基葡萄糖胶囊治疗。治疗组在对照组治疗基础上加用中医推拿和艾灸治疗。两组治疗疗程均为8周。比较两组治疗前后的疗效、视觉模拟评分（VAS）、美国特种外科医院（HSS）评分、世界卫生组织生活质量量表（WHOQOL-BREF）评分、血清高敏C反应蛋白（CRP）及白细胞介素-6（IL-6）水平。

结果

两组患者的年龄、性别、病程比较，差异均无统计学意义（>0.05）。治疗后，治疗组的总有效率显著高于对照组（92.1% vs 78.9%；=0.038）；两组VAS评分均显著降低，且治疗组VAS评分显著低于对照组（3.5±1.4 vs 4.8±1.1；<0.001）；两组HSS评分和WHOQOL-BREF评分均显著改善，且治疗组HSS评分和WHOQOL-BREF评分改善程度优于对照组（<0.05）。两组高敏CRP水平均显著降低，且治疗组高敏CRP水平低于对照组（2.79±1.65 vs 4.37±1.54；<0.001）；治疗组IL-6水平较对照组显著降低（7.22±3.41 vs 4.59±2.98；<0.001）。