The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China.
State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, China.
J Med Virol. 2022 Nov;94(11):5096-5102. doi: 10.1002/jmv.27990. Epub 2022 Jul 22.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), since its outbreak in December 2019, has been capable of continuing the pandemic by mutating itself into different variants. Mass vaccinations, antibiotic treatment therapy, herd immunity, and preventive measures have reduced the disease's severity from the emerging variants. However, the virus is undergoing recombination among the current two variants: Delta and Omicron, resulting in a new variant, informally known as "Deltacron," which was controversial as it might be a product of lab contamination between Omicron and Delta samples. However, the proclamation was proved wrong, and the experts are putting more effort into better understanding the variant's epidemiological characteristics to control potential outbreaks. This review has discussed the potential mutations in the novel variant and prospective risk factors and therapeutic options in the context of this new variant. This study could be used as a guide for implementing appropriate controls in a sudden outbreak of this new variant.
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）自 2019 年 12 月爆发以来，通过自身突变成为不同变体，持续引发大流行。大规模疫苗接种、抗生素治疗、群体免疫和预防措施降低了新变体引发疾病的严重程度。然而，目前两种变体（Delta 和 Omicron）之间的病毒正在重组，导致一种新的变体，非正式地称为“Deltacron”，由于它可能是 Omicron 和 Delta 样本之间实验室污染的产物而备受争议。然而，该说法被证明是错误的，专家们正在努力更好地了解该变体的流行病学特征，以控制潜在的疫情爆发。本综述讨论了新型变体的潜在突变以及在这种新变体情况下的潜在风险因素和治疗选择。本研究可作为在这种新变体突然爆发时实施适当控制的指南。
