Ayón-Aguilar Jorge, Méndez-Martínez Socorro, Toledo-Tapia Ricardo, García-Flores Máximo Alejandro, Mayoral-Ortiz Antonio, Tlecuitl-Mendoza Nataly, Toledo-Tapia Mariana, Ortega-Aguirre Melissa, Amaro-Balderas Eileen
Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada, Coordinación Auxiliar Médica de Investigación en Salud. Puebla, Puebla, México.
Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada, Coordinación de Planeación y Enlace Institucional. Puebla, Puebla, México.
Rev Med Inst Mex Seguro Soc. 2022 Jul 4;60(4):433-439.
The main risk factors studied that have an influence on mortality from COVID-19 have so far been inconclusive in the world literature, mainly in relation to the male gender.
To determine which are the main risk factors that influence a higher mortality from COVID-19.
A case-control study was conducted, including 1190 patients with positive RT-PCR. The risk factors studied were: gender, age, systemic arterial hypertension (SAH), Diabetes mellitus (DM), obesity, Chronic Obstructive Pulmonary Disease (COPD), asthma, smoking, immunosuppressants, Human Immunodeficiency Virus (HIV), influenza vaccine. In the Group of Cases: they died from COVID-19 (n = 576), while in the Controls group: they survived (n = 614). The statistical plan included cross-tables and multivariate logistic regression model to determine the influence of these risk factors on mortality from COVID-19.
We found no statistically significant differences between cases and controls in relation to gender. However, the cases were aged >60 years, SAH, DM, obesity compared to controls.
Male gender was not a risk factor for mortality from COVID-19, however, other risk factors such as age over 60 years, being hypertensive, diabetic and obese, were corroborated as such for a higher mortality from COVID-19.
目前,世界文献中关于对新型冠状病毒肺炎(COVID-19)死亡率有影响的主要研究风险因素尚无定论,主要涉及男性性别方面。
确定哪些是影响COVID-19死亡率更高的主要风险因素。
进行了一项病例对照研究,纳入1190例逆转录聚合酶链反应(RT-PCR)呈阳性的患者。研究的风险因素包括:性别、年龄、系统性动脉高血压(SAH)、糖尿病(DM)、肥胖、慢性阻塞性肺疾病(COPD)、哮喘、吸烟、免疫抑制剂、人类免疫缺陷病毒(HIV)、流感疫苗。病例组:死于COVID-19(n = 576),而对照组:存活(n = 614)。统计方案包括交叉表和多变量逻辑回归模型,以确定这些风险因素对COVID-19死亡率的影响。
我们发现病例组和对照组在性别方面无统计学显著差异。然而,与对照组相比,病例组年龄>60岁、患有SAH、DM、肥胖。
男性性别不是COVID-19死亡的风险因素,然而,其他风险因素,如60岁以上、高血压、糖尿病和肥胖,被证实与COVID-19更高的死亡率相关。