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仿制药市场的价格轨迹:从观察价格轨迹而非平均价格中我们能推断出什么?

Trajectories of prices in generic drug markets: what can we infer from looking at trajectories rather than average prices?

作者信息

Trujillo Antonio J, Gutierrez Jose C, Garcia Morales Emmanuel E, Socal Mariana, Ballreich Jeromie, Anderson Gerard

机构信息

Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA.

Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA.

出版信息

Health Econ Rev. 2022 Jul 11;12(1):37. doi: 10.1186/s13561-022-00384-w.

DOI:10.1186/s13561-022-00384-w
PMID:35819735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9278003/
Abstract

BACKGROUND

Well-functioning competitive markets are key to controlling generic drug prices. This is important since over 90% of all drugs sold in the US are generics. Recently, there have been examples of large price increases in the generic market.

METHODS

This paper examines price trajectories for generic drugs using a group-based trajectory modelling approach (GBTM). We fit the model using quarterly price information in the IBM MarketScan claims database for the past decade.

RESULTS

We identify three dominant price trajectories for this period: rapid increase trajectories, slow decline and rapid decline. Most generic drugs show a slow or a rapid decline in price trajectories. However, around 17% of all generic drugs show rapid price increase trajectories.

CONCLUSIONS

As Congress is exploring an excise tax on drugs whose list price increases faster than the rate of inflation, we discuss what drugs would be most likely to be affected by this law.

摘要

背景

运转良好的竞争市场是控制仿制药价格的关键。这一点很重要,因为在美国销售的所有药品中,超过90%是仿制药。最近,仿制药市场出现了大幅涨价的例子。

方法

本文使用基于群组的轨迹建模方法(GBTM)研究仿制药的价格轨迹。我们利用IBM MarketScan索赔数据库中过去十年的季度价格信息来拟合该模型。

结果

我们确定了这一时期的三种主要价格轨迹:快速上涨轨迹、缓慢下降和快速下降。大多数仿制药的价格轨迹呈缓慢或快速下降趋势。然而,所有仿制药中约有17%呈现快速涨价轨迹。

结论

由于国会正在探讨对标价涨幅超过通货膨胀率的药品征收消费税,我们讨论了哪些药品最有可能受到这项法律的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/c86500b89cd0/13561_2022_384_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/d5a7249e5746/13561_2022_384_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/83daf8c80589/13561_2022_384_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/9d206268e822/13561_2022_384_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/6504ea56456f/13561_2022_384_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/c86500b89cd0/13561_2022_384_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/d5a7249e5746/13561_2022_384_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/83daf8c80589/13561_2022_384_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/9d206268e822/13561_2022_384_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/6504ea56456f/13561_2022_384_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c066/9278003/c86500b89cd0/13561_2022_384_Fig5_HTML.jpg

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Trajectories of prices in generic drug markets: what can we infer from looking at trajectories rather than average prices?仿制药市场的价格轨迹:从观察价格轨迹而非平均价格中我们能推断出什么?
Health Econ Rev. 2022 Jul 11;12(1):37. doi: 10.1186/s13561-022-00384-w.
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本文引用的文献

1
Limited distribution networks stifle competition in the generic and biosimilar drug industries.有限的分销网络扼杀了仿制药和生物类似药行业的竞争。
Am J Manag Care. 2018 Apr 1;24(4):e122-e127.
2
Association of income and prescription drug coverage with generic medication use among older adults with hypertension.收入和处方药保险与老年高血压患者使用通用药物之间的关联。
Am J Manag Care. 2006 Oct;12(10):611-8.
3
Reducing patient drug acquisition costs can lower diabetes health claims.降低患者药品采购成本可降低糖尿病健康索赔。
Am J Manag Care. 2005 Aug;11(5 Suppl):S170-6.