Federman Alex D, Halm Ethan A, Zhu Carolyn, Hochman Tsivia, Siu Albert L
Division of General Internal Medicine, Mount Sinai School of Medicine, 1470 Madison Ave, Box 1087, New York, NY 10029, USA.
Am J Manag Care. 2006 Oct;12(10):611-8.
To determine whether low-income seniors and those without prescription drug coverage are more likely to use generic cardiovascular drugs than more affluent and better insured adults.
Cross-sectional analysis.
We used data from the 2001 Medicare Current Beneficiary Survey. Analyses included noninstitutionalized survey respondents over age 65 years with hypertension who used > or =1 multisource cardiovascular drugs (N = 1710). We examined the association of income and prescription coverage with use of generic versions of multisource drugs from 5 classes: angiotensin-converting enzyme (ACE) inhibitors, beta-adrenergic receptor antagonists (beta-blockers), calcium channel blockers, alpha1-adrenergic receptor antagonists (alpha-blockers), and thiazide diuretics.
Rates of generic medication use were 88.5% (beta-blockers); 92.8% (thiazides); 58.7% (calcium channel blockers); 60.7% (ACE inhibitors); and 52.6% (alpha-blockers). In multivariate analysis of generic medication use aggregated across the 5 drug classes, individuals with incomes below 200% of the federal poverty level were modestly more likely to use generic medications compared with seniors with incomes above 300% of the poverty level. Seniors who lacked prescription coverage were more likely to use generics than those who had employer-sponsored coverage, although the association was of marginal statistical significance (relative risk = 1.29, 95% confidence interval = 1.00, 1.60).
Seniors with low incomes or no prescription coverage were only somewhat more likely to use generic cardiovascular drugs than more affluent and insured seniors. These findings suggest that physicians and policy makers may be missing opportunities to reduce costs for Medicare and its economically disadvantaged beneficiaries.
确定低收入老年人以及没有处方药保险的老年人比富裕且有更好保险的成年人更有可能使用心血管类通用药物。
横断面分析。
我们使用了2001年医疗保险当前受益人调查的数据。分析对象包括年龄在65岁以上、患有高血压且使用过≥1种多源心血管药物的非机构化调查受访者(N = 1710)。我们研究了收入和处方保险与5类多源药物通用版本使用情况之间的关联,这5类药物分别为:血管紧张素转换酶(ACE)抑制剂、β-肾上腺素能受体拮抗剂(β受体阻滞剂)、钙通道阻滞剂、α1-肾上腺素能受体拮抗剂(α受体阻滞剂)和噻嗪类利尿剂。
通用药物的使用率分别为:88.5%(β受体阻滞剂);92.8%(噻嗪类);58.7%(钙通道阻滞剂);60.7%(ACE抑制剂);以及52.6%(α受体阻滞剂)。在对这5类药物通用药物使用情况进行的多变量分析中,收入低于联邦贫困线200%的个体与收入高于贫困线300%的老年人相比,使用通用药物的可能性略高。缺乏处方保险的老年人比有雇主提供保险的老年人更有可能使用通用药物,尽管这种关联在统计学上具有边际显著性(相对风险 = 1.29,95%置信区间 = 1.00,1.60)。
低收入或无处方保险的老年人使用心血管类通用药物的可能性仅比富裕且有保险的老年人略高。这些发现表明,医生和政策制定者可能错失了降低医疗保险及其经济弱势受益人的成本的机会。