Department of Veterinary Surgery, Faculty of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Department of Animal Medicine (Internal Medicine), Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.
Open Vet J. 2022 May-Jun;12(3):356-359. doi: 10.5455/OVJ.2022.v12.i3.8. Epub 2022 May 31.
Portal vein thrombosis is a disease with potentially deleterious outcomes including portal vein hypertension and intestinal infarction. The factors contributing is various; however, dogs with with acute portal vein thrombosis or multiple thromboses are less likely to survive. Therefore, acute development of portal hypertension has a requires an immediate treatment.
A 10-year-old Dalmatian was referred for syncope and azotemia, hyperammonemia. After each examinations including computed tomography scan, we diagnosed with acute portal vein thrombosis with unknown cause. A portal vein port was inserted to prevent and control the portal vein thrombus. The port was placed in abdomen subcutaneously after the position of the catheter were stabilized. Low-molecular-weight heparin was injected from the port to manage thrombosis after the operation. This case responded well to this treatment. Syncope and azotemia, hyperammonemia resolved and no relapse of thrombosis was found 6 months after the operation.
Implantable vascular access port is a drug delivery system with the advantage of dealing with treatment-resistant acute portal vein thrombosis.
门静脉血栓形成是一种可能导致严重后果的疾病，包括门静脉高压和肠梗死。其致病因素多种多样；然而，患有急性门静脉血栓形成或多发性血栓形成的狗存活的可能性较小。因此，门静脉高压的急性发展需要立即治疗。
一只 10 岁的斑点狗因晕厥和氮质血症、血氨升高而被转介。在包括计算机断层扫描在内的各项检查后，我们诊断为不明原因的急性门静脉血栓形成。为了预防和控制门静脉血栓，我们插入了门静脉端口。在导管位置稳定后，将端口放置在腹部皮下。术后，从端口注入低分子肝素以治疗血栓形成。该病例对这种治疗反应良好。术后 6 个月，晕厥、氮质血症、血氨升高得到缓解，未发现血栓复发。
植入式血管通路端口是一种药物输送系统，具有治疗耐药性急性门静脉血栓形成的优势。
