Prakash Aaditya, Upadhyay Amitabh
Radiation Oncology, Tata Main Hospital, Jamshedpur, IND.
Oncology, Tata Main Hospital, Jamshedpur, IND.
Cureus. 2022 Jun 10;14(6):e25812. doi: 10.7759/cureus.25812. eCollection 2022 Jun.
Cutaneous metastasis (CM) of head-and-neck squamous cell carcinoma is rarely reported. Here, we report a case of a 78-year-old male who had already had a surgically treated case of carcinoma of the right buccal mucosa one and a half months back but presented with a near local site recurrence and subsequently developed distant skin metastases to the lower neck and upper trunk during treatment. Local site recurrence was confirmed with a biopsy, but benign-looking lesions in the lower neck and upper trunk were developed during the last week of treatment, which later on kept growing in size and after the biopsy came positive for malignancy. Although there was a complete response at the recurred site of malignancy, there was a progression of disease at the initially benign-looking lesion in the lower neck and upper trunk, which later on was proven to be cutaneous malignancy on histopathology. This case has cemented the fact that the chance of the presence of occult skin metastasis at the time of diagnosis in primary or recurrent malignancies. Thus, tissue biopsy should be done with a high index of suspicion for cutaneous malignancy associated with head and neck cancers.
头颈部鳞状细胞癌的皮肤转移（CM）鲜有报道。在此，我们报告一例78岁男性病例，该患者一个半月前曾接受过右侧颊黏膜癌手术治疗，但出现了局部近位复发，随后在治疗期间发生了远处皮肤转移至下颈部和上躯干。局部复发经活检确诊，但在治疗的最后一周下颈部和上躯干出现了外观良性的病变，这些病变随后不断增大，活检后证实为恶性。尽管恶性复发部位出现了完全缓解，但下颈部和上躯干最初外观良性的病变出现了疾病进展，后来经组织病理学证实为皮肤恶性肿瘤。该病例进一步证实了在原发性或复发性恶性肿瘤诊断时存在隐匿性皮肤转移的可能性。因此，对于与头颈部癌症相关的皮肤恶性肿瘤，应高度怀疑并进行组织活检。
