Zatula D G, Bikhunov V L, Iudin V M
Eksp Onkol. 1987;9(2):33-6.
The level of proliferative activity is studied in the cells of thymus, spleen and lymphoid nodes of mice with transplanted OH-2 tumour once- or thrice-immunized with vaccines from syngeneic tumour cells. Single immunization is shown to induce the short-term modulation of the proliferative processes in lymphoid organs and to increase somewhat the level of antitumour resistance of vaccinized mice. The triple-inoculation of vaccines evokes a more pronounced rise in the level of the proliferative activity in cells of lymphoid organs.
在将OH-2肿瘤移植到小鼠体内后，对用同基因肿瘤细胞疫苗单次或三次免疫的小鼠的胸腺、脾脏和淋巴结细胞中的增殖活性水平进行了研究。结果表明，单次免疫可诱导淋巴器官中增殖过程的短期调节，并在一定程度上提高接种疫苗小鼠的抗肿瘤抵抗力水平。三次接种疫苗会使淋巴器官细胞中的增殖活性水平有更明显的升高。
