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嗅觉功能客观检查的应用研发

[Application research and development of objective examination of olfactory function].

作者信息

DU Weijia, Chen Fuquan

机构信息

Department of Otolaryngology Head and Neck Surgery,Xijing Hospital,Air Force Medical University,Xi'an,710032,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Jun;36(6):482-486. doi: 10.13201/j.issn.2096-7993.2022.06.016.

Abstract

The sense of smell is one of the five most primitive human sensory functions, and it plays a very important role in our daily lives. Despite numerous methods for evaluating olfactory function, there is still a lack of standardization of olfactory tests and the results are often inconsistent. Furthermore, the related research on objective evaluation started relatively late. Along with the deciphering of the olfactory pathway, the technical level of olfactory objective inspection has been greatly improved and significant progress has also been made in terms of clinical application, such as: olfactory pathway MRI and fMRI imaging, OERPs, BEAM for various olfactory disorders and early diagnosis of neurodegenerative disorders, as well as related research based on bionic olfactory sensing technology. This article mainly introduces the recent research progress of several commonly used objective olfactory tests and provides reference for more accurate evaluation of olfactory function.

摘要

嗅觉是人类最原始的五种感官功能之一,在我们的日常生活中起着非常重要的作用。尽管有众多评估嗅觉功能的方法,但嗅觉测试仍缺乏标准化,结果往往不一致。此外,客观评估的相关研究起步相对较晚。随着嗅觉通路的破译,嗅觉客观检查的技术水平有了很大提高,在临床应用方面也取得了显著进展,如:嗅觉通路MRI和fMRI成像、嗅觉事件相关电位(OERPs)、各种嗅觉障碍和神经退行性疾病早期诊断的脑电地形图(BEAM),以及基于仿生嗅觉传感技术的相关研究。本文主要介绍几种常用客观嗅觉测试的最新研究进展,为更准确地评估嗅觉功能提供参考。

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