[肾上腺素和去甲肾上腺素对猫脑、肾、肠及后肢器官血流变化的比较分析]
[Comparative analysis of the changes in the organic blood flow in the brain, kidneys, intestines and hindlimbs of cats as affected by adrenaline and noradrenaline].
作者信息
Beketov A I, Korneliuk I K
出版信息
Farmakol Toksikol. 1987 Mar-Apr;50(2):33-6.
PMID:3582630
Abstract
In experiments on anesthetized cats by using the method of hydrogen clearance it was found that noradrenaline and adrenaline at doses of 0.01-10 micrograms/kg intravenously produced dose-dependent various changes in organ blood flow that were caused by differences in the action on adrenoreceptors and the degree of hypertensive reaction. The vessels of the intestine and kidneys possessed the highest sensitivity to noradrenaline and the cerebral vessels had the least sensitivity.
摘要
在用氢清除法对麻醉猫进行的实验中发现，静脉注射剂量为0.01 - 10微克/千克的去甲肾上腺素和肾上腺素会产生剂量依赖性的器官血流变化，这些变化是由对肾上腺素能受体的作用差异和高血压反应程度引起的。肠道和肾脏的血管对去甲肾上腺素最为敏感，而脑血管的敏感性最低。
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