[咖啡因和昔多芬对抗立位应激期间脑、肾及后肢血液供应的影响]
[Effect of caffeine and sidnofen on the blood supply of the brain, kidneys and hindlimbs during antiorthostatism].
作者信息
Koniaeva E I, Beketov A I
出版信息
Farmakol Toksikol. 1987 May-Jun;50(3):39-42.
PMID:3609274
Abstract
The method of hydrogen clearance was used in experiments on anesthetized cats for studying changes in the blood flow in the brain, kidneys and vena cava caudalis under prolonged antiorthostatism (45 degrees) and medication with caffeine and sidnofen. Specific features of the organ blood flow redistribution under the influence of antiorthostatism and the drugs administered before and after placement of the animals in the antiorthostatic position were established.
摘要
采用氢清除法，在麻醉猫身上进行实验，以研究长时间（45度）头低位倾斜及使用咖啡因和西地那非药物时，大脑、肾脏和尾腔静脉的血流变化。确定了头低位倾斜以及动物置于头低位前后给药影响下器官血流重新分布的具体特征。
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