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2007-2017 年巴西圣卡塔琳娜州母婴传播 HIV 病例的时间趋势和空间分布:一项生态学研究。

Temporal trend and spatial distribution of cases of mother-to-child transmission of HIV in the state of Santa Catarina, Brazil, 2007-2017: an ecological study.

机构信息

Universidade do Sul de Santa Catarina, Programa de Pós-Graduação em Ciências da Saúde, Tubarão, SC, Brasil.

Governo do Estado de Santa Catarina, Diretoria de Vigilância Epidemiológica, Florianópolis, SC, Brasil.

出版信息

Epidemiol Serv Saude. 2022 Jul 6;31(2):e2021877. doi: 10.1590/S2237-96222022000100009. eCollection 2022.

DOI:10.1590/S2237-96222022000100009
PMID:35830006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9887967/
Abstract

OBJECTIVE

To analyze the temporal trend and spatial distribution of mother-to-child HIV transmission in Santa Catarina between 2007 and 2017.

METHODS

This was a mixed ecological study with data from the Notifiable Health Conditions Information System. Linear regression was performed for time series analysis and the mean rates in the period and mean annual percentage changes in the rates of HIV-infected pregnant women were calculated, children exposed to HIV during pregnancy, and seroconversion of children exposed to HIV/AIDS during pregnancy, in addition to data geoprocessing.

RESULTS

There were 5,554 records of HIV-infected pregnant women, with a rate of 5.6 pregnant women per 1,000 live births. The mean seroconversion rate was 13.5/100,000 live births (95%CI 6.8;20.1) and it showed a falling trend (APC = -99.4%; 95%CI -99.9;-93.1). The seroconversion rate was more expressive in small towns.

CONCLUSION

The rate of HIV-infected pregnant women was stable in the period, whereas the number of children infected with HIV through mother-to-child transmission decreased.

摘要

目的

分析 2007 年至 2017 年间圣卡塔琳娜州母婴 HIV 传播的时间趋势和空间分布。

方法

这是一项混合生态研究,数据来自法定传染病信息系统。对时间序列进行线性回归分析,计算该时期内 HIV 感染孕妇、妊娠期间暴露于 HIV 的儿童以及妊娠期间暴露于 HIV/AIDS 的儿童的血清转化率的平均率以及平均年百分率变化,并进行数据地理处理。

结果

共记录了 5554 例 HIV 感染孕妇,每 1000 例活产中有 5.6 例孕妇。血清转化率的平均值为 13.5/100,000 活产(95%CI 6.8;20.1),呈下降趋势(APC = -99.4%;95%CI -99.9;-93.1)。血清转化率在小镇更为明显。

结论

该时期 HIV 感染孕妇的比例保持稳定,而通过母婴传播感染 HIV 的儿童数量有所减少。

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