From the Center for Urogynecology and Pelvic Reconstructive Surgery, Women's Health Institute.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Urogynecology (Phila). 2022 Oct 1;28(10):649-657. doi: 10.1097/SPV.0000000000001227. Epub 2022 Jul 2.
The intraoperative resting genital hiatus (GH) size can be surgically modified but its relationship to prolapse recurrence is unclear.
The objective of this study was to identify the optimal intraoperative resting GH size as it relates to prolapse recurrence and functional outcomes at 1 year.
This prospective cohort study was conducted at 2 hospitals from 2019 to 2021. Intraoperative measurements of the resting GH, perineal body, and total vaginal length were collected. The composite primary outcome consisted of anatomic recurrence, subjective recurrence, and/or conservative or surgical retreatment at 1 year. Comparisons of anatomic, functional, and sexual outcomes were compared between patients stratified by the optimal intraoperative GH size identified by receiver operating characteristic curve analysis.
Sixty-eight patients (median age of 63 years) underwent surgery, with 59 (86.8%) presenting for follow-up at 1 year. Based on the 13 patients (22%) with composite recurrence, receiver operating characteristic curve analysis demonstrated an intraoperative resting GH size of 3 cm, had 76.9% sensitivity (confidence interval [CI], 54-99.8%), and 34.8% specificity (CI, 21.0-48.5%) for composite recurrence at 1 year (area under curve = 0.61). Nineteen patients had an intraoperative GH less than 3 cm (32.2%) and 40 had a GH of 3 cm or greater (67.8%). The intraoperative resting GH size was significantly larger in patients with prolapse beyond the hymen at 1 year (4 cm [3.0, 4.0]) compared with those with prolapse at or proximal to the hymen (3.0 cm [2.5, 3.5], P = 0.009).
Intraoperative GH size may not reliably predict composite prolapse recurrence at 1 year, although there was an association between intraoperative resting GH size with prolapse beyond the hymen.
术中静息生殖器裂孔(GH)大小可以手术改变,但与脱垂复发的关系尚不清楚。
本研究旨在确定与 1 年时脱垂复发和功能结局相关的最佳术中静息 GH 大小。
这是一项前瞻性队列研究,于 2019 年至 2021 年在 2 家医院进行。收集术中静息 GH、会阴体和阴道总长度的测量值。复合主要结局包括 1 年后的解剖学复发、主观复发和/或保守或手术治疗。根据接受者操作特征曲线分析确定的最佳术中 GH 大小,对患者进行分层,比较解剖学、功能和性功能结局。
68 例患者(中位年龄 63 岁)接受了手术,59 例(86.8%)在 1 年时进行了随访。根据 13 例(22%)复合复发患者的情况,接受者操作特征曲线分析显示,术中静息 GH 大小为 3cm 时,对 1 年时的复合复发有 76.9%的敏感性(置信区间[CI],54%-99.8%)和 34.8%的特异性(CI,21.0%-48.5%)(曲线下面积=0.61)。19 例患者术中 GH 小于 3cm(32.2%),40 例患者 GH 大于或等于 3cm(67.8%)。与处女膜内脱垂的患者相比,1 年后 GH 超过处女膜的患者术中静息 GH 大小显著更大(4cm[3.0, 4.0]),与处女膜近端或处女膜内脱垂的患者相比(3cm[2.5, 3.5]),P=0.009)。
术中 GH 大小可能不能可靠地预测 1 年后的复合脱垂复发,但术中静息 GH 大小与处女膜外脱垂之间存在关联。