人羊水对人羊膜超滤液中前列腺素E生成的刺激作用。

Stimulation of prostaglandin E production in superfused human amnion by human amniotic fluid.

作者信息

Strickland D M, Mitchell M D

出版信息

Gynecol Obstet Invest. 1987;23(1):23-7. doi: 10.1159/000298829.

Abstract

We studied the effects of human amniotic fluid (HAF) on the production of prostaglandin E (PGE) by amnion tissues using a technique of fresh-tissue superfusion. The production of PGE was linear with time for 4.5 h by amnion tissues superfused either with medium alone or with medium plus HAF (30% v/v). Tissues superfused with medium plus HAF produced significantly more PGE than tissues superfused with medium alone. Additionally, amnion tissue obtained at cesarean section, prior to labor, displayed a greater responsiveness to HAF than did amnion obtained after spontaneous labor.

摘要

我们采用新鲜组织灌流技术研究了人羊水（HAF）对羊膜组织前列腺素E（PGE）产生的影响。单独用培养基或用培养基加HAF（30%体积/体积）灌流的羊膜组织，PGE的产生在4.5小时内与时间呈线性关系。用培养基加HAF灌流的组织比单独用培养基灌流的组织产生的PGE显著更多。此外，剖宫产时在临产前提取的羊膜组织对HAF的反应性比自然分娩后获取的羊膜组织更强。