From the Department of Dermatology (Bin Rubaian, Al Zamami, Almuhaidib), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, and from the Department of Dermatology (Al Breiki), King Fahad Hospital of the University, Khobar, Kingdom of Saudi Arabia.
Saudi Med J. 2022 Jul;43(7):751-754. doi: 10.15537/smj.2022.43.7.20220352.
Genital lymphedema usually develops after 4-30 years of chronic hidradenitis suppurativa (HS). However, our patient exhibited signs of it as early as 2 years after being diagnosed with HS. Renal amyloidosis is a rarely reported complication of HS. Unfortunately, our patient was asymptomatic but was found to have end-stage renal disease secondary to advanced renal amyloidosis. We report a case of a 42-year-old Indian gentleman who had HS for 9 years presenting with 2 rare complications: penoscrotal lymphedema and end-stage renal disease secondary to renal amyloidosis. The patient was treated with prednisolone and adalimumab to treat both his HS and renal amyloidosis, and was referred to general surgery to manage his genital lymphedema. We recommend following adult patients with moderate-to-severe HS and clinical duration of greater than 3 years and screening for amyloidosis before they reach end-stage organ disease, similar to what happened to our patient with end-stage renal disease.
生殖器淋巴水肿通常在慢性化脓性汗腺炎（HS）后 4-30 年内发展。然而，我们的患者在被诊断为 HS 后仅 2 年就出现了这种迹象。肾淀粉样变性是 HS 罕见的并发症。不幸的是，我们的患者无症状，但发现患有晚期肾淀粉样变性引起的终末期肾病。我们报告了一例 42 岁的印度男子，他患有 HS 9 年，出现了 2 种罕见的并发症：阴茎阴囊淋巴水肿和继发于肾淀粉样变性的终末期肾病。该患者接受了泼尼松龙和阿达木单抗治疗以治疗其 HS 和肾淀粉样变性，并被转介到普通外科手术以治疗其生殖器淋巴水肿。我们建议对患有中重度 HS 且临床病程大于 3 年的成年患者进行随访，并在达到终末期器官疾病之前筛查淀粉样变性，就像我们的终末期肾病患者一样。
